Molecular structure of Methyl gallate, CAS Number: 99-24-1
Methyl gallate (CAS 99-24-1)
Alternate Names:
Methyl 3,4,5-trihydroxybenzoate
CAS Number:
99-24-1
Purity:
≥98%
Molecular Weight:
184.15
Molecular Formula:
C8H8O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Methyl gallate is a compound that functions as an antioxidant in experimental applications. It acts by scavenging free radicals and inhibiting oxidative stress at the molecular level. Methyl Gallate is known to chelate metal ions, thereby preventing them from catalyzing the production of reactive oxygen species. Methyl gallate also exhibits anti-inflammatory properties by modulating the expression of pro-inflammatory cytokines and enzymes. It may possess antimicrobial activity, disrupting the cell membranes of microorganisms and inhibiting their growth. Methyl gallate inhibits certain enzymes involved in lipid metabolism, suggesting a potential role in lipid-lowering effects.
Methyl gallate (CAS 99-24-1) References
- Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. | Lee, H., et al. 2010. J Immunol. 185: 6698-705. PMID: 21048105
- Methyl Gallate Inhibits Osteoclast Formation and Function by Suppressing Akt and Btk-PLCγ2-Ca2+ Signaling and Prevents Lipopolysaccharide-Induced Bone Loss. | Baek, JM., et al. 2017. Int J Mol Sci. 18: PMID: 28272351
- Potential usefulness of methyl gallate in the treatment of experimental colitis. | Anzoise, ML., et al. 2018. Inflammopharmacology. 26: 839-849. PMID: 29116460
- Methyl gallate: Selective antileishmanial activity correlates with host-cell directed effects. | Noleto Dias, C., et al. 2020. Chem Biol Interact. 320: 109026. PMID: 32112863
- Methyl gallate attenuates inflammation induced by Toll-like receptor ligands by inhibiting MAPK and NF-Κb signaling pathways. | Correa, LB., et al. 2020. Inflamm Res. 69: 1257-1270. PMID: 33037469
- Methyl Gallate Attenuates Doxorubicin-Induced Cardiotoxicity in Rats by Suppressing Oxidative Stress. | Ahmed, AZ., et al. 2021. Scientifica (Cairo). 2021: 6694340. PMID: 33510932
- Methyl gallate, gallic acid-derived compound, inhibit cell proliferation through increasing ROS production and apoptosis in hepatocellular carcinoma cells. | Huang, CY., et al. 2021. PLoS One. 16: e0248521. PMID: 33725002
- Anti-glycation activities of methyl gallate in vitro and in human explants. | Shin, S., et al. 2022. J Cosmet Dermatol. 21: 2602-2609. PMID: 34418257
- Methyl Gallate Improves Hyperuricemia Nephropathy Mice Through Inhibiting NLRP3 Pathway. | Liu, P., et al. 2021. Front Pharmacol. 12: 759040. PMID: 34987391
- Protective effect of methyl gallate on murine antigen-induced arthritis by inhibiting inflammatory process and bone erosion. | Correa, LB., et al. 2022. Inflammopharmacology. 30: 251-266. PMID: 35112275
- Effect of Methyl Gallate on 1-Nitropyrene-Induced Keratinocyte Toxicity in a Human and Canine Skin Model. | Lee, WJ., et al. 2022. J Microbiol Biotechnol. 32: 869-876. PMID: 35880479
- Methyl Gallate Suppresses Tumor Development by Increasing Activation of Caspase3 and Disrupting Tumor Angiogenesis in Melanoma. | Park, JK., et al. 2022. Evid Based Complement Alternat Med. 2022: 6295910. PMID: 36110191
- Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway. | Zhou, P., et al. 2022. Int J Mol Sci. 23: PMID: 36430509
- Antimelanogenesis Effect of Methyl Gallate through the Regulation of PI3K/Akt and MEK/ERK in B16F10 Melanoma Cells. | Cheng, ZJ., et al. 2022. Evid Based Complement Alternat Med. 2022: 5092655. PMID: 36532851
- Methyl gallate nanomicelles impairs neutrophil accumulated in zymosan-induced arthritis. | Pereira, LM., et al. 2023. Colloids Surf B Biointerfaces. 227: 113351. PMID: 37244202
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl gallate, 50 g | sc-269572 | 50 g | $83.00 |