Date published: 2026-1-12

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Methyl Diethyldithiocarbamate (CAS 686-07-7)

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Alternate Names:
N,N-Diethylcarbamodithioic Acid Methyl Ester; Diethyldithiocarbamic Acid Methyl Ester
Application:
Methyl Diethyldithiocarbamate is a metabolite of mixed disulfide S-(N,N-diethyldithiocarbamoyl)-N-acetyl-L-cysteine (AC-DDTC), which is an antimutagenic mixed disulfide from disulfram
CAS Number:
686-07-7
Molecular Weight:
163.30
Molecular Formula:
C6H13NS2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl diethyldithiocarbamate interacts with cellular components by binding to metal ions, particularly copper and zinc, within the cell. This interaction disrupts the normal function of these metal ions, leading to inhibition of various cellular processes. Methyl diethyldithiocarbamate interferes with the activity of metalloenzymes. This disruption ultimately leads to impaired cellular respiration and energy production. Methyl diethyldithiocarbamate induces oxidative stress within the cell, leading to damage of cellular components such as proteins, lipids, and DNA. Methyl diethyldithiocarbamate also influences cellular signaling pathways, particularly those involved in regulating cell growth and survival. The interaction of methyl diethyldithiocarbamate with cellular components leads to significant disruption of normal cellular function and can ultimately result in cell death.


Methyl Diethyldithiocarbamate (CAS 686-07-7) References

  1. Effect of thiocarbonyl compounds on alpha-naphthylisothiocyanate-induced hepatotoxicity and the urinary excretion of [35S]alpha-naphthylisothiocyanate in the rat.  |  Traiger, GJ., et al. 1984. Toxicol Appl Pharmacol. 72: 504-12. PMID: 6324415
  2. Inhibition of aldehyde dehydrogenase by disulfiram and its metabolite methyl diethylthiocarbamoyl-sulfoxide.  |  Veverka, KA., et al. 1997. Biochem Pharmacol. 53: 511-8. PMID: 9105402

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl Diethyldithiocarbamate, 250 mg

sc-470888
250 mg
$401.00