Methyl a-D-mannopyranoside (CAS 617-04-9)

Methyl α-D-mannopyranoside is a methylated sugar derivative extensively used in biochemical and structural research. This compound serves as a model substrate for studying glycosidase enzymes, particularly α-mannosidases, which catalyze the hydrolysis of α-mannosidic linkages in glycoproteins and glycolipids. By using methyl α-D-mannopyranoside in enzyme assays, researchers can investigate the kinetic properties, substrate specificity, and catalytic mechanisms of these enzymes. Additionally, it aids in the elucidation of the structure-function relationships of α-mannosidases through crystallographic studies. Methyl α-D-mannopyranoside is also employed in glycosylation studies to probe the synthesis and modification of glycan structures in various biological systems. In membrane biology, it is used to understand the binding interactions between mannose-specific lectins and their ligands, providing insights into cell-cell recognition and adhesion processes. Furthermore, this compound is utilized in the synthesis of mannose-containing oligosaccharides and glycosides, facilitating the exploration of carbohydrate chemistry and the development of novel glycomimetics. Its role in these diverse research areas underscores its importance as a tool for advancing knowledge in enzymology, glycobiology, and structural biology, contributing to a deeper understanding of carbohydrate-mediated biological processes.