Molecular structure of Methyl 5-nitro-2-furoate, CAS Number: 1874-23-3
Methyl 5-nitro-2-furoate (CAS 1874-23-3)
Alternate Names:
5-Nitro-2-furancarboxylic acid methyl ester
CAS Number:
1874-23-3
Molecular Weight:
171.11
Molecular Formula:
C6H5NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Methyl 5-nitro-2-furoate functions as a nitrofuran derivative that can undergo reduction to form reactive intermediates, which can then interact with cellular macromolecules such as DNA and proteins. This interaction can lead to the formation of adducts and DNA cross-links, potentially interfering with DNA replication and transcription processes. The nitro group can undergo reduction to form nitro anion radicals, which can participate in redox cycling reactions, leading to the generation of reactive oxygen species and subsequent oxidative stress within the cell.
Methyl 5-nitro-2-furoate (CAS 1874-23-3) References
- Formation of novel nitrofuran metabolites in xanthine oxidase-catalyzed reduction of methyl 5-nitro-2-furoate. | Yamada, H., et al. 1984. Arch Biochem Biophys. 232: 234-9. PMID: 6547583
- Reduction of methyl 5-nitro-2-furoate by xanthine oxidase: an evidence for hydroxylaminofuran formation. | Yamada, H., et al. 1982. Chem Pharm Bull (Tokyo). 30: 2647-50. PMID: 7139825
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl 5-nitro-2-furoate, 1 g | sc-228559 | 1 g | $29.00 |