Date published: 2025-12-3

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methyl 5-formyl-2-furoate (CAS 5904-71-2)

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Alternate Names:
methyl 5-formylfuran-2-carboxylate
CAS Number:
5904-71-2
Molecular Weight:
154.12
Molecular Formula:
C7H6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl 5-formyl-2-furoate is involved in the process of DNA repair. It acts as a substrate for the enzyme formamidopyrimidine-DNA glycosylase (Fpg), which is responsible for recognizing and removing damaged bases from DNA. Methyl 5-formyl-2-furoate is recognized by Fpg as a lesion resulting from oxidative damage to DNA. Upon recognition, Fpg cleaves the glycosidic bond between the damaged base and the sugar-phosphate backbone, initiating the base excision repair pathway. The ability of Fpg to recognize and process methyl 5-formyl-2-furoate highlights its importance in the cellular response to oxidative stress. Methyl 5-formyl-2-furoate contributes to the maintenance of genomic stability and the preservation of genetic information.


methyl 5-formyl-2-furoate (CAS 5904-71-2) References

  1. Chemicals from renewables: aerobic oxidation of furfural and hydroxymethylfurfural over gold catalysts.  |  Taarning, E., et al. 2008. ChemSusChem. 1: 75-8. PMID: 18605666
  2. Synthesis of Furandicarboxylic Acid Esters From Nonfood Feedstocks Without Concomitant Levulinic Acid Formation.  |  van der Klis, F., et al. 2017. ChemSusChem. 10: 1460-1468. PMID: 28124823
  3. A biocatalytic approach towards sustainable furanic–aliphatic polyesters  |  Jiang, Y., Woortman, A. J., van Ekenstein, G. O. A., & Loos, K. 2015. Polymer Chemistry,. 6: 5198-5211.
  4. Hydroxyapatite supported gold nanocatalyst for base-free oxidative esterification of 5-hydroxymethyl-2-furfural to 2, 5-furan dimethylcarboxylate with air as oxidant  |  Mishra, D. K., Cho, J. K., Yi, Y., Lee, H. J., & Kim, Y. J. 2019. Journal of Industrial and Engineering Chemistry. 70: 338-345.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

methyl 5-formyl-2-furoate, 250 mg

sc-353995
250 mg
$309.00

methyl 5-formyl-2-furoate, 1 g

sc-353995A
1 g
$523.00