Date published: 2026-5-13

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Methyl 5-aminosalicylate (CAS 42753-75-3)

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CAS Number:
42753-75-3
Molecular Weight:
167.16
Molecular Formula:
C8H9NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl 5-aminosalicylate is a synthetic preservative. It exists as a white, odorless, crystalline powder that readily dissolves in water and alcohol. Methylparaben, an ester derived from p-hydroxybenzoic acid, serves the purpose of inhibiting the growth of bacteria and fungi in various products. In scientific research, Methyl 5-aminosalicylate finds has been utilized in investigating the effects of preservatives on cell cultures, exploring the impact of preservatives on the growth of bacteria and fungi, assessing the stability of proteins in the presence of preservatives, and examining the stability of lipids under similar conditions.


Methyl 5-aminosalicylate (CAS 42753-75-3) References

  1. [Teratologic studies of methyl 5-aminosalicylate and salicylazopyridine].  |  Xiong, JM., et al. 1992. Zhongguo Yao Li Xue Bao. 13: 265-7. PMID: 1359731
  2. Selective COX-2 inhibitors. Part 2: synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides.  |  Lin, SJ., et al. 2008. Bioorg Med Chem. 16: 2697-706. PMID: 18063374
  3. [Therapeutic effect of methyl 5-aminosalicylate on experimental ulcerative colitis in rabbits].  |  Liao, YZ., et al. 1990. Zhongguo Yao Li Xue Bao. 11: 54-6. PMID: 1976289
  4. Development of o-chlorophenyl substituted pyrimidines as exceptionally potent aurora kinase inhibitors.  |  Lawrence, HR., et al. 2012. J Med Chem. 55: 7392-7416. PMID: 22803810
  5. Design, Synthesis, and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors.  |  Cotman, AE., et al. 2017. Arch Pharm (Weinheim). 350: PMID: 28621824
  6. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.  |  Abdu-Allah, HHM., et al. 2020. Bioorg Chem. 94: 103378. PMID: 31677858

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl 5-aminosalicylate, 1 g

sc-235791
1 g
$63.00