Date published: 2025-9-30

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Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide (CAS 35511-14-9)

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Application:
CAS Number:
35511-14-9
Molecular Weight:
255.25
Molecular Formula:
C10H9NO5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide, also known as Piroxicam impurity G, is a benzothiazine derivative that has been found in Piroxicam formulations. Piroxicam is a non-steroidal anti-inflammatory compound that may act to act as a non-selective COX inhibitor. Other benzothiazine dioxide analogues have been shown to act as potent calpain I inhibitors making this compound of interest to researchers.


Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide (CAS 35511-14-9) References

  1. 1,2-Benzothiazine 1,1-dioxide alpha-ketoamide analogues as potent calpain I inhibitors.  |  Bihovsky, R., et al. 2004. Bioorg Med Chem Lett. 14: 1035-8. PMID: 15013018
  2. Synthesis and antiinflammatory activity of some 3-carboxamides of 2-alkyl-4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide.  |  Lombardino, JG., et al. 1971. J Med Chem. 14: 1171-5. PMID: 5116229

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide, 500 mg

sc-207871
500 mg
$612.00