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Methyl 4-Azidotetrafluorobenzoate (CAS 122590-75-4)

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Alternate Names:
4-Azido-2,3,5,6-tetrafluorobenzoic Acid Methyl Ester; Methyl 4-Azido-2,3,5,6-tetrafluorobenzoate
Application:
Methyl 4-Azidotetrafluorobenzoate is a protected photoaffinity reagent
CAS Number:
122590-75-4
Molecular Weight:
249.13
Molecular Formula:
C8H3F4N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl 4-Azidotetrafluorobenzoate is studied for its applications in the synthesis of complex organic molecules and the modification of various substrates through click chemistry. Its role in facilitating the creation of covalent bonds between diverse molecular entities is highly valued in materials science and bioconjugation techniques. Researchers focus on its potential in the development of advanced materials, including photoresists, due to its reactivity when exposed to specific wavelengths of light. Furthermore, the compound′s utility in attaching molecular probes to biomolecules makes it an important tool in the field of chemical biology, aiding in the visualization and study of biological processes. Methyl 4-Azidotetrafluorobenzoate is also instrumental in the preparation of fluorinated compounds, which have numerous applications due to their unique properties.


Methyl 4-Azidotetrafluorobenzoate (CAS 122590-75-4) References

  1. Facile and efficient synthesis of 4-azidotetrafluoroaniline: a new photoaffinity reagent.  |  Chehade, KA. and Spielmann, HP. 2000. J Org Chem. 65: 4949-53. PMID: 10956477
  2. A universal protocol for photochemical covalent immobilization of intact carbohydrates for the preparation of carbohydrate microarrays.  |  Wang, H., et al. 2011. Bioconjug Chem. 22: 26-32. PMID: 21138274
  3. Direct grafting of tetraaniline via perfluorophenylazide photochemistry to create antifouling, low bio-adhesion surfaces.  |  Lin, CW., et al. 2019. Chem Sci. 10: 4445-4457. PMID: 31057772
  4. Accessing Perfluoroaryl Sulfonimidamides and Sulfoximines via Photogenerated Perfluoroaryl Nitrenes: Synthesis and Application as a Chiral Auxiliary.  |  Proietti, G., et al. 2021. J Org Chem. 86: 17119-17128. PMID: 34766772
  5. New reagents for photoaffinity labeling: synthesis and photolysis of functionalized perfluorophenyl azides  |  Keana, J. F., & Cai, S. X. 1990. The Journal of Organic Chemistry. 55(11): 3640-3647.
  6. Introduction of functional groups into polymer films via deep-UV photolysis or electron-beam lithography: modification of polystyrene and poly (3-octylthiophene) by a functionalized perfluorophenyl azide.  |  Cai, S. X., Kanskar, M., Wybourne, M. N., & Keana, J. F. 1992. Chemistry of materials. 4(4): 879-884.
  7. Chemistry of Bifunctional Photoprobes: 4. Synthesis of the Chromogenic, Cleavable, Water Soluble, and Heterobifunctional Sulfosuccinimidyl (N-methylamino Perfluoroaryl Azido Benzamido)-ethyl-1, 3′-Dithiopropionate: An Efficient Protein Cross-Linking Agent  |  Pandurangi, R. S., Lusiak, P., Desai, S., & Kuntz, R. R. 1998. Bioorganic Chemistry. 26(4): 201-212.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl 4-Azidotetrafluorobenzoate, 100 mg

sc-211857
100 mg
$300.00