Molecular structure of Methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside, CAS Number: 59571-75-4
Methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside (CAS 59571-75-4)
Application:
Methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside is a substrate for the linkage-specific 1,2-α-mannosidase
CAS Number:
59571-75-4
Molecular Weight:
356.30
Molecular Formula:
C13H24O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside (MMP) is a substrate for the linkage-specific 1,2-alpha-mannosidase (MAN1) from Aspergillus niger. In vitro studies have demonstrated that it can inhibit the production of pro-inflammatory cytokines and chemokines and induce apoptosis in cancer cells. In biotechnology and material science, Methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside serves as a substrate for enzymes in glycosylation reactions and as a building block for synthesizing novel polymers and materials.
Methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside (CAS 59571-75-4) References
- Molecular and enzymic properties of recombinant 1, 2-alpha-mannosidase from Aspergillus saitoi overexpressed in Aspergillus oryzae cells. | Ichishima, E., et al. 1999. Biochem J. 339 (Pt 3): 589-97. PMID: 10215597
- Man alpha1-2 Man alpha-OMe-concanavalin A complex reveals a balance of forces involved in carbohydrate recognition. | Moothoo, DN., et al. 1999. Glycobiology. 9: 539-45. PMID: 10336986
- Class I alpha-mannosidases are required for N-glycan processing and root development in Arabidopsis thaliana. | Liebminger, E., et al. 2009. Plant Cell. 21: 3850-67. PMID: 20023195
- Prediction of the anomeric configuration, type of linkage, and residues in disaccharides from 1D (13)C NMR data. | Pereira, F. 2011. Carbohydr Res. 346: 960-72. PMID: 21440245
- Characterization of putative glycosylphosphatidylinositol-anchoring motifs for surface display in the methylotrophic yeast Hansenula polymorpha. | Cheon, SA., et al. 2014. Biotechnol Lett. 36: 2085-94. PMID: 24930114
- Glycosidases of Aspergillus niger. 3. Purification and characterization of 1,2- -mannosidase. | Swaminathan, N., et al. 1972. J Biol Chem. 247: 1775-9. PMID: 5012761
- Spectroscopic studies on the interaction of pradimicin BMY-28864 with mannose derivatives. | Fujikawa, K., et al. 1998. Glycobiology. 8: 407-14. PMID: 9499388
- Synthesis and conformational analysis of methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside | Peters, T. 1991. Liebigs Annalen Der Chemie. 1991(2): 135-141.
- The potential energy surface of methyl 2‐O‐(α‐d‐mannopyranosyl)‐α‐d‐mannopyranoside in aqueous solution: Conclusions derived from optical rotation | Stevens, E. S. 1994. Biopolymers: Original Research on Biomolecules. 34(10): 1403-1407.
Substrate of:
MAN1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl 2-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside, 5 mg | sc-221895 | 5 mg | $326.00 |