Date published: 2025-10-14

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Methyl 2-hydroxy-3-methylbenzoate (CAS 23287-26-5)

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Alternate Names:
2-Hydroxy-3-methylbenzoic acid methyl ester; Methyl 3-methylsalicylate
CAS Number:
23287-26-5
Molecular Weight:
166.17
Molecular Formula:
C9H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl 2-hydroxy-3-methylbenzoate involves the inhibition of specific enzymes, particularly cyclooxygenase-2 (COX-2). By targeting COX-2, this compound effectively hinders the production of prostaglandins, which are inflammatory molecules. Through this inhibition, Methyl 2-hydroxy-3-methylbenzoate can effectively alleviate inflammation and alleviate associated pain. By impeding the production of prostaglandins, this compound exerts its anti-inflammatory and analgesic effects.


Methyl 2-hydroxy-3-methylbenzoate (CAS 23287-26-5) References

  1. Synthesis and anticancer activities of 3-arylflavone-8-acetic acid derivatives.  |  Yan, GH., et al. 2015. Eur J Med Chem. 90: 251-7. PMID: 25461325
  2. Photolabile acetals as profragrances: the effect of structural modifications on the light-induced release of volatile aldehydes on cotton.  |  Trachsel, A., et al. 2016. Photochem Photobiol Sci. 15: 1183-1203. PMID: 27509886
  3. Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines.  |  Castelli, R., et al. 2020. J Med Chem. 63: 1261-1280. PMID: 31714779
  4. Spirocyclopropane compounds. III. Synthesis of spiro[benzofuran-2(3H),1'-cyclopropan]-3-ones for evaluation as gastric antisecretory and antiulcer agents.  |  Kawada, M., et al. 1984. Chem Pharm Bull (Tokyo). 32: 3532-50. PMID: 6525649
  5. Rate Acceleration of Nucleophilic Substitution of 2-Chloro-4,6-dimethoxypyrimidine by Sulfinate Catalysis  |  Y Bessard, R Crettaz. 2000. Tetrahedron. 56: 4739-4745.
  6. Pd(OAc)2-catalyzed orthogonal synthesis of 2-hydroxybenzoates and substituted cyclohexanones from acyclic unsaturated 1,3-carbonyl compounds  |  T Miyagi, S Okada, N Tada, M Sugihara, N Kagawa. 2019. Tetrahedron Letters. 60: 1653-1657.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl 2-hydroxy-3-methylbenzoate, 2 g

sc-279341
2 g
$80.00