Methyl 2-Deoxy-2-N-phthalimido-3,4,6-tri-O-acetyl-β-D-glucopyranoside (CAS 76101-13-8)

Methyl 2-deoxy-2-N-phthalimido-3,4,6-tri-O-acetyl-β-D-glucopyranoside serves as a valuable chemical tool in glycoscience research due to its structural complexity and versatility. Its primary application lies in the synthesis and study of glycosides, which are crucial biomolecules involved in various biological processes, including cell-cell recognition, signaling, and immune response modulation. Researchers utilize this compound to investigate glycosylation reactions and enzymatic transformations mediated by glycosyltransferases, glycosidases, and other carbohydrate-modifying enzymes. Specifically, methyl 2-deoxy-2-N-phthalimido-3,4,6-tri-O-acetyl-β-D-glucopyranoside is employed as a glycosyl donor or acceptor substrate in enzymatic assays to explain the substrate specificity, catalytic mechanisms, and kinetics of glycosyltransferases and glycosidases. Furthermore, its triply acetylated glucoside moiety provides chemical protection and facilitates selective deprotection strategies during glycosylation reactions, allowing for the synthesis of complex oligosaccharides and glycoconjugates with precise regio- and stereochemistry. This compound also finds utility in the development of glycosylation methodologies, glycan array fabrication, and glycomics research aimed at deciphering the roles of glycans in health and disease. Overall, methyl 2-deoxy-2-N-phthalimido-3,4,6-tri-O-acetyl-β-D-glucopyranoside serves as a fundamental building block for exploring carbohydrate biology and advancing our understanding of glycan-mediated processes in biological systems.