Date published: 2026-5-1

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Methyl 2-amino-5-fluorobenzoate (CAS 319-24-4)

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Alternate Names:
4-Fluoro-2-(methoxycarbonyl)aniline; Methyl 5-fluoroanthranilate
CAS Number:
319-24-4
Molecular Weight:
169.15
Molecular Formula:
C8H8FNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl 2-amino-5-fluorobenzoate (MAFB) is a versatile organic compound with a multitude of applications in scientific and industrial fields. This colorless and odorless crystalline solid possesses exceptional properties, such as solubility in water and polar solvents, making it highly valuable in various contexts. Primarily, Methyl 2-amino-5-fluorobenzoate serves as a intermediate compound in the synthesis of diverse organic compounds. Its role extends to being a reagent, facilitating organic synthesis, and functioning as a catalyst in organic reactions. Scientists have employed Methyl 2-amino-5-fluorobenzoate in studying biochemical and physiological processes of vital importance. Moreover, the compound has attracted attention for its ability to modulate the activity of enzymes and proteins. Methyl 2-amino-5-fluorobenzoate acts as an agonist for the G-protein coupled receptor GPR17, which regulates cell proliferation and differentiation. Its inhibitory effects on tyrosine kinase, an enzyme involved in cell growth and differentiation regulation, have also been observed.


Methyl 2-amino-5-fluorobenzoate (CAS 319-24-4) References

  1. Design, synthesis, and evaluation of nonretinoid retinol binding protein 4 antagonists for the potential treatment of atrophic age-related macular degeneration and Stargardt disease.  |  Cioffi, CL., et al. 2014. J Med Chem. 57: 7731-57. PMID: 25210858

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl 2-amino-5-fluorobenzoate, 5 g

sc-263506
5 g
$53.00

Methyl 2-amino-5-fluorobenzoate, 25 g

sc-263506A
25 g
$215.00