Methoxypolyethylene glycol maleimide (CAS 99126-64-4)
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Methoxypolyethylene glycol maleimide (mPEG-Mal) serves as a pivotal reagent in the field of bioconjugation chemistry, facilitating the attachment of polyethylene glycol (PEG) chains to molecules, with a particular emphasis on proteins. This process, known as PEGylation, enhances the solubility and stability of proteins, significantly extending their presence and function within research environments. The maleimide group of Methoxypolyethylene glycol maleimide reacts specifically with thiol groups (–SH) found on cysteine residues in proteins, forming stable thioether bonds. This specificity allows for controlled modification of proteins without altering their biological activity, making Methoxypolyethylene glycol maleimide an invaluable tool in the development of protein-based assays and in the study of protein dynamics and interactions. Its role in research extends beyond mere chemical modification, contributing to advancements in the understanding of protein behavior in various biological applications.
Methoxypolyethylene glycol maleimide (CAS 99126-64-4) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methoxypolyethylene glycol maleimide, 1 g | sc-228469 | 1 g | $213.00 |