Methoxypolyethylene glycol amine (CAS 80506-64-5)
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Methoxypolyethylene glycol amine is a compound extensively used in polymer and materials science research. It serves as a versatile reagent for the modification of surfaces and the preparation of polymer conjugates due to the presence of both a polyethylene glycol (PEG) moiety and an amine group. The PEG segment of methoxypolyethylene glycol amine provides water solubility and biocompatibility, which is in the study of stealth coatings for nanoparticles used in non-clinical experimental applications. Researchers exploit the amine functionality to link MPEG-amine to various molecules or surfaces, thereby enabling the conjugation of certain chemicals, dyes, or targeting ligands to PEGylated carriers. Additionally, methoxypolyethylene glycol amine is used in the synthesis of block copolymers, where it can form part of the hydrophilic block, contributing to the understanding of self-assembly and micelle formation in solution.
Methoxypolyethylene glycol amine (CAS 80506-64-5) References
- PEG-appended beta-(1-->3)-D-glucan schizophyllan to deliver antisense-oligonucleotides with avoiding lysosomal degradation. | Karinaga, R., et al. 2005. Biomaterials. 26: 4866-73. PMID: 15763266
- In vitro and in vivo characterization of nanoparticles made of MeO-PEG amine/PLA block copolymer and PLA. | Sasatsu, M., et al. 2006. Int J Pharm. 317: 167-74. PMID: 16621360
- A PEGylated fluorescent turn-on sensor for detecting fluoride ions in totally aqueous media and its imaging in live cells. | Zheng, F., et al. 2013. Chemistry. 19: 936-42. PMID: 23197478
- One-step reduction and PEGylation of graphene oxide for photothermally controlled drug delivery. | Chen, J., et al. 2014. Biomaterials. 35: 4986-95. PMID: 24656608
- Polyethylene glycol-conjugated chondroitin sulfate A derivative nanoparticles for tumor-targeted delivery of anticancer drugs. | Lee, JY., et al. 2016. Carbohydr Polym. 151: 68-77. PMID: 27474544
- Fabricating Triple-Sensitive Polymer Nano-Aggregates via an Aqueous Iminoboronate Multicomponent Reaction. | Liu, Y., et al. 2017. Macromol Rapid Commun. 38: PMID: 28217874
- Fluorinated PEG-Polypeptide Polyplex Micelles Have Good Serum-Resistance and Low Cytotoxicity for Gene Delivery. | Wu, T., et al. 2017. Macromol Biosci. 17: PMID: 28524376
- Amplification-free, sequence-specific 16S rRNA detection at 1 aM. | Koo, B., et al. 2018. Lab Chip. 18: 2291-2299. PMID: 29987290
- Radioactive lutetium metallofullerene 177LuxLu(3-x)N@C80-PCBPEG derivative: a potential tumor-targeted theranostic agent. | Zhang, G., et al. 2015. J Mater Chem B. 3: 7011-7013. PMID: 32262702
- Ionic Species Affect the Self-Propulsion of Urease-Powered Micromotors. | Arqué, X., et al. 2020. Research (Wash D C). 2020: 2424972. PMID: 32803169
- A peptide-based coating toolbox to enable click chemistry on polymers, metals, and silicon through sortagging. | Nöth, M., et al. 2021. Biotechnol Bioeng. 118: 1520-1530. PMID: 33404092
- Omega-3 production by fish oil hydrolysis using a lipase from Burkholderia gladioli BRM58833 immobilized and stabilized by post-immobilization techniques. | Martins, PA., et al. 2022. Biochem Biophys Rep. 29: 101193. PMID: 35128079
- Antioxidant PDA-PEG nanoparticles alleviate early osteoarthritis by inhibiting osteoclastogenesis and angiogenesis in subchondral bone. | Wu, Z., et al. 2022. J Nanobiotechnology. 20: 479. PMID: 36384720
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methoxypolyethylene glycol amine, 250 mg | sc-253011 | 250 mg | $113.00 |