Date published: 2026-4-24

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Methoxyamine hydrochloride (CAS 593-56-6)

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Alternate Names:
O-Methylhydroxylamine hydrochloride; Methoxylammonium Chloride
Application:
Methoxyamine hydrochloride is a reagent for the preparation of O-methyl oximes
CAS Number:
593-56-6
Purity:
≥97%
Molecular Weight:
83.52
Molecular Formula:
CH5NO•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methoxyamine hydrochloride is a reagent for the preparation of O-methyl oximes. The compound acts by combining with human antithrombin III-thrombin complex to form an inactive thrombin. It covalently binds to apurinic/apyrimidinic DNA damage sites and thereby inhibits base excision repair (BER) process, which may prevent repair of DNA strand breaks and result in an induction of apoptosis. This agent may potentiate the anti-tumor activity of alkylating agents.


Methoxyamine hydrochloride (CAS 593-56-6) References

  1. Determination of steroids in bovine hair: Validation of a microwave-assisted chemical derivatization method using liquid chromatography-tandem mass spectrometry and in vivo studies.  |  Rocha, DG., et al. 2020. Drug Test Anal. 12: 1078-1086. PMID: 32384229
  2. Determination of Steroids in Bovine Serum: Validation of a Reliable LC-MS/MS Method and In Vivo Studies with Boldenone Undecylenate and Testosterone Propionate.  |  Rocha, DG., et al. 2020. J Agric Food Chem. 68: 11545-11552. PMID: 32960588
  3. Analysis of Soluble Sugar Content in Minute Quantities of Rice Tissues by GC-MS.  |  Xu, LH., et al. 2021. Bio Protoc. 11: e4077. PMID: 34327274
  4. Metabonomics Study in Mice With Learning and Memory Impairment on the Intervention of Essential Oil Extracted From Cinnamomum camphora Chvar. Borneol.  |  Tang, Y., et al. 2022. Front Pharmacol. 13: 770411. PMID: 35359846
  5. Synthesis, Characterization and Catalytic Property Studies for Isoprene Polymerization of Iron Complexes Bearing Unionized Pyridine-Oxime Ligands.  |  Zhao, M., et al. 2022. Polymers (Basel). 14: PMID: 36080685
  6. Mulberry (Morus alba L.) Leaf Extract and 1-Deoxynojirimycin Improve Skeletal Muscle Insulin Resistance via the Activation of IRS-1/PI3K/Akt Pathway in db/db Mice.  |  Kang, CW., et al. 2022. Life (Basel). 12: PMID: 36295064
  7. Carboxylic Acid Isostere Derivatives of Hydroxypyridinones as Core Scaffolds for Influenza Endonuclease Inhibitors.  |  Stokes, RW., et al. 2023. ACS Med Chem Lett. 14: 75-82. PMID: 36655124
  8. Some Lessons Learned on the Impact of the Storage Conditions, Syringe Wash Solvent, and the Way of GC-MS Injection on the Reproducibility of Metabolomic Studies.  |  Kurbatov, I., et al. 2023. Metabolites. 13: PMID: 36677000
  9. Hepatocellular Metabolic Abnormalities Induced by Long-Term Exposure to Novel Brominated Flame Retardant, Hexabromobenzene.  |  Shin, B., et al. 2023. Toxics. 11: PMID: 36850976
  10. Comprehensive Study of Components and Antimicrobial Properties of Essential Oil Extracted from Carum carvi L. Seeds.  |  Liu, C., et al. 2023. Antibiotics (Basel). 12: PMID: 36978458
  11. In situ microwave fixation provides an instantaneous snapshot of the brain metabolome.  |  Juras, JA., et al. 2023. Cell Rep Methods. 3: 100455. PMID: 37159672
  12. Integrating multiomics data accelerates elucidation of plant primary and secondary metabolic pathways.  |  Zhu, F., et al. 2023. aBIOTECH. 4: 47-56. PMID: 37220537
  13. GC-MS based untargeted metabolomics reveals the metabolic response of earthworm (Eudrilus eugeniae) after chronic combinatorial exposure to three different pesticides.  |  Malla, MA., et al. 2023. Sci Rep. 13: 8583. PMID: 37237073

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methoxyamine hydrochloride, 1 g

sc-257710
1 g
$34.00

Methoxyamine hydrochloride, 5 g

sc-257710A
5 g
$71.00