Molecular structure of Methiothepin mesylate salt, CAS Number: 74611-28-2
Methiothepin mesylate salt (CAS 74611-28-2)
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Application:
Methiothepin mesylate salt is a 5-HT1/6/7 receptor antagonist
CAS Number:
74611-28-2
Purity:
≥98%
Molecular Weight:
452.65
Molecular Formula:
C20H24N2S2•CH3SO3H
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Methiothepin mesylate salt, a methanesulfonate salt form of methiothepin, is a compound of interest within the field of neurochemistry and psychopharmacology research, primarily for its potent antagonist activity on serotonin receptors. This compound serves as a tool in the investigation of the serotonergic system′s role in various neural processes, including mood regulation, cognition, and neural network modulation. By blocking serotonin receptors, methiothepin mesylate provides a means to study the effects of serotonin inhibition on animal models, thus offering insights into the complex mechanisms of neurotransmission and potential targets for modulating these pathways.
Methiothepin mesylate salt (CAS 74611-28-2) References
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- Novel and Potent 5-Piperazinyl Methyl-N 1-aryl Sulfonyl Indole Derivatives as 5-HT6 Receptor Ligands. | Nirogi, RV., et al. 2010. ACS Med Chem Lett. 1: 340-4. PMID: 24900216
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- Serotonergic Drugs Inhibit Chikungunya Virus Infection at Different Stages of the Cell Entry Pathway. | Bouma, EM., et al. 2020. J Virol. 94: PMID: 32321803
- Seasonal and daily variations in the plasma gonadotropin II response to a LHRH analog and serotonin in Atlantic croaker (Micropogonias undulatus): evidence for mediation by 5-HT2 receptors. | Khan, IA. and Thomas, P. 1994. J Exp Zool. 269: 531-7. PMID: 7931125
- 5-Hydroxytryptophan-induced myoclonus in guinea pigs: mediation through 5-HT1/2 receptor subtypes. | Pappert, EJ., et al. 1998. Eur J Pharmacol. 347: 51-6. PMID: 9650847
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Inhibitor of:
CREB-2, SR-1A, SR-1F, SR-6, SR-7, and TPH2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methiothepin mesylate salt, 100 mg | sc-253005 | 100 mg | $141.00 |