Date published: 2026-4-24

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Methanesulfonic acid (CAS 75-75-2)

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CAS Number:
75-75-2
Purity:
≥99%
Molecular Weight:
96.11
Molecular Formula:
CH4O3S
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methanesulfonic acid (MSA), a strong organic acid, is produced in large quantities through the chemical oxidation of dimethyl sulfide in the atmosphere. This green acid undergoes biodegradation, forming CO2 and sulfate. Unlike mineral acids, Methanesulfonic acid is less toxic and corrosive, making it an environmentally friendly option. Its aqueous solution is used as a representative electrolyte in electrochemical processes.The product offered is a 70% aqueous solution of methanesulfonic acid (MSA), a powerful organic acid. Methanesulfonic acid is generated in significant amounts through the chemical oxidation of dimethyl sulfide in the atmosphere. This compound can biodegrade into CO2 and sulfate. In comparison to mineral acids, Methanesulfonic acid is considered a green acid due to its lower toxicity and corrosiveness. Moreover, its aqueous solution serves as a model electrolyte for electrochemical processes. Methanesulfonic acid, also known as Methanesulfonate or Methanesulfonic acid, chromium (2+) salt, falls into the category of organosulfonic acids. These acids contain the sulfonic acid group with the general structure RS(=O)2OH (where R is not a hydrogen atom). Methanesulfonic acid is soluble in water and displays acidic properties.


Methanesulfonic acid (CAS 75-75-2) References

  1. Methanesulfonic acid sodium salt protects retina from acute light damage in mice.  |  Wang, HY., et al. 2012. Chin Med J (Engl). 125: 2310-5. PMID: 22882854
  2. Methanesulfonic acid salt forms of carbamazepine and 10,11-dihydrocarbamazepine.  |  Eberlin, AR., et al. 2013. Acta Crystallogr C. 69: 1260-6. PMID: 24192169
  3. Structure and vibrational spectroscopy of methanesulfonic acid.  |  Zhong, L. and Parker, SF. 2018. R Soc Open Sci. 5: 181363. PMID: 30662741
  4. Significant Underestimation of Gaseous Methanesulfonic Acid (MSA) over Southern Ocean.  |  Yan, J., et al. 2019. Environ Sci Technol. 53: 13064-13070. PMID: 31670933
  5. Methanesulfonic Acid-driven New Particle Formation Enhanced by Monoethanolamine: A Computational Study.  |  Shen, J., et al. 2019. Environ Sci Technol. 53: 14387-14397. PMID: 31710478
  6. Synthesis of Methanesulfonic Acid Directly from Methane: The Cation Mechanism or the Radical Mechanism?  |  Li, H., et al. 2021. J Phys Chem Lett. 12: 6486-6491. PMID: 34240874
  7. Clusteromics II: Methanesulfonic Acid-Base Cluster Formation.  |  Elm, J. 2021. ACS Omega. 6: 17035-17044. PMID: 34250361
  8. Effect of Hydration on Electron Attachment to Methanesulfonic Acid Clusters.  |  Pysanenko, A., et al. 2022. J Phys Chem A. 126: 1542-1550. PMID: 35230848
  9. Amine-Enhanced Methanesulfonic Acid-Driven Nucleation: Predictive Model and Cluster Formation Mechanism.  |  Liu, Y., et al. 2022. Environ Sci Technol. 56: 7751-7760. PMID: 35593326
  10. Electrochemically Initiated Synthesis of Methanesulfonic Acid.  |  Britschgi, J., et al. 2022. Angew Chem Int Ed Engl. 61: e202209591. PMID: 35972467
  11. Contribution of Methanesulfonic Acid to the Formation of Molecular Clusters in the Marine Atmosphere.  |  Rasmussen, FR., et al. 2022. J Phys Chem A. 126: 7127-7136. PMID: 36191242
  12. Photoelectrochemical Behavior of WO3 in an Aqueous Methanesulfonic Acid Electrolyte.  |  Jakubow-Piotrowska, K., et al. 2022. ACS Phys Chem Au. 2: 299-304. PMID: 36855420
  13. Role of Methanesulfonic Acid in Sulfuric Acid-Amine and Ammonia New Particle Formation.  |  Johnson, JS. and Jen, CN. 2023. ACS Earth Space Chem. 7: 653-660. PMID: 36960424

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methanesulfonic acid, 25 g

sc-215308
25 g
$40.00

Methanesulfonic acid, 100 g

sc-215308A
100 g
$54.00

Methanesulfonic acid, 500 g

sc-215308B
500 g
$193.00

Methanesulfonic acid, 1 kg

sc-215308C
1 kg
$255.00