METH Antibody (4E2): sc-58375

METH Antibody (4E2) is a mouse monoclonal IgG1 antibody that detects METH protein of non-species reactive by enzyme-linked immunosorbent assay (ELISA). Anti-METH antibody (4E2) is available as a non-conjugated format. Methamphetamine (METH) is a potent central nervous system stimulant that not only enhances alertness and energy but also has significant peripheral sympathomimetic effects. Chemically related to amphetamine, METH has been utilized in clinical settings for various conditions, including narcolepsy, depression, obesity, and to alleviate fatigue. METH protein, with a molecular weight of 149.2 g/mol, selectively binds to specific receptors, triggering cellular responses that are crucial for neurotransmitter release. METH′s mechanism of action involves the release of newly synthesized norepinephrine and dopamine while simultaneously blocking their re-uptake, resulting in elevated concentrations of catecholamines in the synaptic cleft. This action is particularly important as it can lead to neurotoxicity, primarily affecting the dopaminergic system within the striatum, which is associated with various neuropsychiatric disorders. METH is often misused as a recreational drug, contributing to widespread abuse and highlighting the need for effective detection methods, such as those provided by METH (4E2) antibody.

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METH Antibody (4E2) References:

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