Molecular structure of Met Kinase Inhibitor, CAS Number: 658084-23-2
Met Kinase Inhibitor (CAS 658084-23-2)
See product citations (5)
Alternate Names:
(3Z)-N-(3-Chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide; SU11274
Application:
Met Kinase Inhibitor is a competitive inhibitor of Met kinase activity
CAS Number:
658084-23-2
Purity:
≥98%
Molecular Weight:
568.1
Molecular Formula:
C28H30ClN5O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Met Kinase Inhibitor is a pyrrole indolinone compound acting as an ATP-competitive inhibitor of Met kinase activity. Met Kinase Inhibitor shows great (>60-fold) selectivity over Flk and Ron, FGFR-1, c-Src, Cdk2, PDGFRβ, EGFR, and Tie-2 (>400-fold). Met Kinase Inhibitor demonstrated inhibitory effects on HGF/SF-stimulated cellular signaling and Med-mediated tumorigenisis.
Inhibitor of:
BAI-2, CMTM8, DPY19L1, E1AF, HGF, HGFL α, MACC1, Met, PMPCB, robo4, and SEMA3E.Activator of:
EphA6, Eps15, and PRPF4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Met Kinase Inhibitor, 1 mg | sc-204801 | 1 mg | $116.00 |