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Mesoridazine besylate (CAS 32672-69-8)

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Alternate Names:
Mesoridazine benzenesulfonate
Application:
Mesoridazine besylate is a D2DR and D4DR inhibitor
CAS Number:
32672-69-8
Molecular Weight:
544.75
Molecular Formula:
C21H26N2OS2•C6H6O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Mesoridazine besylate is a phenothiazine dopamine receptor antagonist. Mesoridazine is described to demonstrate inhibition for D2DR and D4DR. Mesoridazine besylate works by blocking dopamine receptors in the brain, and is known for anticholinergic effects.


Mesoridazine besylate (CAS 32672-69-8) References

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  2. Diastereotopic analysis of mesoridazine besylate (Serentil).  |  Morrow, RJ., et al. 2004. Chirality. 16: 534-40. PMID: 15290689
  3. Comparison of the effects of thioridazine and mesoridazine on the QT interval in healthy adults after single oral doses.  |  Salih, IS., et al. 2007. Clin Pharmacol Ther. 82: 548-54. PMID: 17410120
  4. Pharmaceutical salts: a summary on doses of salt formers from the Orange Book.  |  Saal, C. and Becker, A. 2013. Eur J Pharm Sci. 49: 614-23. PMID: 23747999
  5. Identification of novel chemotherapeutic strategies for metastatic uveal melanoma.  |  Fagone, P., et al. 2017. Sci Rep. 7: 44564. PMID: 28303962
  6. Cardiotoxic manifestations of mesoridazine overdose.  |  Marrs-Simon, PA., et al. 1988. Ann Emerg Med. 17: 1074-8. PMID: 3177997
  7. Liquid chromatographic determination of organic nitrogenous bases in dosage forms: a progress report.  |  Walker, ST. 1985. J Assoc Off Anal Chem. 68: 539-42. PMID: 4019383
  8. Sexual dysfunction associated with mesoridazine besylate (serentil).  |  Shader, RI. 1972. Psychopharmacologia. 27: 293-4. PMID: 4674517
  9. High-performance liquid chromatographic assay for nanogram determination of chlorpromazine and its comparison with a radioimmunoassay.  |  Midha, KK., et al. 1981. J Pharm Sci. 70: 1043-6. PMID: 6101152
  10. The metabolism of piperidine-type phenothiazine antipsychotic agents. III. Mesoridazine in dog, human and rat.  |  Lin, G., et al. 1993. Xenobiotica. 23: 37-52. PMID: 8097900
  11. Familial Creutzfeldt-Jakob disease with a five-repeat octapeptide insert mutation.  |  Cochran, EJ., et al. 1996. Neurology. 47: 727-33. PMID: 8797471
  12. Free radical scavenging enzyme activity and related trace metals in clozapine-induced agranulocytosis: a pilot study.  |  Linday, LA., et al. 1995. J Clin Psychopharmacol. 15: 353-60. PMID: 8830067
  13. Water intoxication in a patient with the Prader-Willi syndrome treated with desmopressin for nocturnal enuresis.  |  Robson, WL., et al. 1997. J Urol. 157: 646-7. PMID: 8996389

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Mesoridazine besylate, 10 mg

sc-500471
10 mg
$118.00

Mesoridazine besylate, 25 mg

sc-500471A
25 mg
$397.00