Molecular structure of Mesna, CAS Number: 19767-45-4
Mesna (CAS 19767-45-4)
See product citations (2)
Alternate Names:
Sodium 2-mercaptoethanesulfonate; Uromitexan; 2-Mercaptoethanesulfonic acid Sodium Salt
Application:
Mesna is a compound that reacts with acrolein and other urotoxic metabolites to form stable, non-urotoxic compounds
CAS Number:
19767-45-4
Purity:
≥98%
Molecular Weight:
164.18
Molecular Formula:
C2H5O3S2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Mesna functions as a detoxifying agent in experiment. Mesna works by forming stable conjugates with the toxic metabolites, rendering them less harmful. Mesna′s function as a detoxifying agent is particularly relevant in experimental contexts where the potential for toxic metabolite formation is a concern.
Mesna (CAS 19767-45-4) References
- Ifosfamide and mesna. | Schoenike, SE. and Dana, WJ. 1990. Clin Pharm. 9: 179-91. PMID: 2107997
- The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats. | Li, X., et al. 2013. J Gynecol Oncol. 24: 177-85. PMID: 23653836
- The cytogenetic action of ifosfamide, mesna, and their combination on peripheral rabbit lymphocytes: an in vivo/in vitro cytogenetic study. | Bogiatzi, S., et al. 2014. Cytotechnology. 66: 753-60. PMID: 23949582
- Chemically assisted dissection by means of mesna in cholesteatoma surgery. | Vincenti, V., et al. 2014. Otol Neurotol. 35: 1819-24. PMID: 25025536
- Pharmacokinetics of intravenous and oral sodium 2-mercaptoethane sulphonate (mesna) in normal subjects. | James, CA., et al. 1987. Br J Clin Pharmacol. 23: 561-8. PMID: 3109461
- [8] and [10]-Gingerol reduces urothelial damage in ifosfamide-induced hemorrhagic cystitis via JAK/STAT/FOXO signaling pathway via IL-10. | Ferreira, FCS., et al. 2023. Naunyn Schmiedebergs Arch Pharmacol. 396: 1773-1786. PMID: 36843129
- Defluoroalkylation of Trifluoromethylarenes with Hydrazones: Rapid Access to Benzylic Difluoroarylethylamines. | Hendy, CM., et al. 2023. Org Lett. 25: 1397-1402. PMID: 36848497
- Alkyl Thiocyanurates as Thioester Mimetics. Transthioesterification and Ligation Reactions with High Potential in Dynamic Covalent Chemistry. | Wołczański, G., et al. 2023. J Org Chem. 88: 8192-8202. PMID: 37329497
- Spasmolytic and Uroprotective Effects of Apigenin by Downregulation of TGF-β and iNOS Pathways and Upregulation of Antioxidant Mechanisms: In Vitro and In Silico Analysis. | Saima, ., et al. 2023. Pharmaceuticals (Basel). 16: PMID: 37375759
- Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study. | Vinknes, KJ., et al. 2023. Diabetes Obes Metab.. PMID: 37435697
- Fabrication of impedimetric sensor based on metallic nanoparticle for the determination of mesna anticancer drug. | Mehrban, M., et al. 2023. Sci Rep. 13: 11381. PMID: 37452101
- Clinical studies on the mucolytic effect of mesna. | Tekeres, M., et al. 1981. Clin Ther. 4: 56-60. PMID: 6791825
- Studies on the urotoxicity of oxazaphosphorine cytostatics and its prevention--III. Profile of action of sodium 2-mercaptoethane sulfonate (mesna). | Brock, N., et al. 1982. Eur J Cancer Clin Oncol. 18: 1377-87. PMID: 6819957
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mesna, 5 g | sc-218697 | 5 g | $94.00 |