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Mesaconic acid (CAS 498-24-8)

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Alternate Names:
Methylfumaric acid
CAS Number:
498-24-8
Purity:
99%
Molecular Weight:
130.10
Molecular Formula:
C5H6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Mesaconic acid indeed has a chemical formula of C5H6O4. It is a dicarboxylic acid with a molecular weight of 130.1 g/mol. Mesaconic acid is a geometric isomer of maleic acid. It is used in various industrial applications, including the production of polymers, resins, and pharmaceutical intermediates.. It serves as a metabolite in both humans and plants. Mesaconic acid is formed from fumaric acid and acts as the conjugate acid of mesaconate(2-). It plays various biological roles and is involved in metabolic processes in both human and plant organisms.


Mesaconic acid (CAS 498-24-8) References

  1. Note on the isolation of mesaconic acid from cabbage leaves.  |  Buston, HW. 1928. Biochem J. 22: 1523-5. PMID: 16744171
  2. The reaction of anthracene with maleic and fumaric acid and their derivatives and with citraconic anhydride and mesaconic acid.  |  BACHMANN, WE. and SCOTT, LB. 1948. J Am Chem Soc. 70: 1458-61. PMID: 18915764
  3. Quantitative analysis of citric acid/sodium hypophosphite modified cotton by HPLC and conductometric titration.  |  Ye, T., et al. 2015. Carbohydr Polym. 121: 92-8. PMID: 25659676
  4. High-level production of ethylmalonyl-CoA pathway-derived dicarboxylic acids by Methylobacterium extorquens under cobalt-deficient conditions and by polyhydroxybutyrate negative strains.  |  Sonntag, F., et al. 2015. Appl Microbiol Biotechnol. 99: 3407-19. PMID: 25661812
  5. Green Synthesis of a New Al-MOF Based on the Aliphatic Linker Mesaconic Acid: Structure, Properties and In Situ Crystallisation Studies of Al-MIL-68-Mes.  |  Reinsch, H., et al. 2018. Chemistry. 24: 2173-2181. PMID: 29227561
  6. A Transcription Factor-Based Biosensor for Detection of Itaconic Acid.  |  Hanko, EKR., et al. 2018. ACS Synth Biol. 7: 1436-1446. PMID: 29638114
  7. LC-MS based urinary metabolomics study of the intervention effect of aloe-emodin on hyperlipidemia rats.  |  Ji, H., et al. 2018. J Pharm Biomed Anal. 156: 104-115. PMID: 29698861
  8. Modular Enzymatic Cascade Synthesis of Vitamin B5 and Its Derivatives.  |  Abidin, MZ., et al. 2018. Chemistry. 24: 17434-17438. PMID: 30192043
  9. Straightforward Synthetic Protocol to Bio-BasedUnsaturated Poly(ester amide)s from Itaconic Acidwith Thixotropic Behavior.  |  Papadopoulos, L., et al. 2020. Polymers (Basel). 12: PMID: 32331487
  10. Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism.  |  Chen, F., et al. 2022. Nat Metab. 4: 534-546. PMID: 35655026
  11. Improvement of dicarboxylic acid production with Methylorubrum extorquens by reduction of product reuptake.  |  Pöschel, L., et al. 2022. Appl Microbiol Biotechnol. 106: 6713-6731. PMID: 36104545
  12. New metabolites in isovaleric acidemia.  |  Truscott, RJ., et al. 1981. Clin Chim Acta. 110: 187-203. PMID: 6452974
  13. 3-Methylaspartate ammonia-lyase from a facultative anaerobe, strain YG-1002.  |  Kato, Y. and Asano, Y. 1995. Appl Microbiol Biotechnol. 43: 901-7. PMID: 7576557

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Mesaconic acid, 10 g

sc-255263
10 g
$115.00

Mesaconic acid, 50 g

sc-255263A
50 g
$312.00