Merocyanine 540 (CAS 62796-23-0)
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Merocyanine 540 serves as a notable fluorescent axonal stain, distinguished by its unique mechanism of action that involves intercalating into lipid bilayers, where it preferentially associates with certain lipid environments. This property makes it especially useful in neuroscience research for visualizing and tracking the intricate networks of axons within nervous tissue. By binding selectively to components of the neuronal membrane, Merocyanine 540 facilitates the observation of axonal processes in real time, enabling researchers to study the dynamic aspects of axonal guidance, nerve injury response, and the architectural organization of neural circuits. Its fluorescence capabilities allow for high-resolution imaging techniques, such as confocal microscopy, to be employed, providing valuable insights into the fundamental processes that govern neural development and function. The application of Merocyanine 540 in research thus offers a powerful tool for elucidating the complex interactions within neural systems, contributing significantly to the advancement of neuroscientific knowledge.
Merocyanine 540 (CAS 62796-23-0) References
- Merocyanine 540 as an optical probe of transmembrane electrical activity in the heart. | Salama, G. and Morad, M. 1976. Science. 191: 485-7. PMID: 1082169
- Merocyanine 540 as a fluorescent probe of altered membrane phospholipid asymmetry in activated whole blood platelets. | Watala, C., et al. 2002. Cytometry. 49: 119-33. PMID: 12442312
- Merocyanine 540 as a probe to monitor the molecular packing of phosphatidylcholine: a monolayer epifluorescence microscopy and spectroscopy study. | Yu, H. and Hui, SW. 1992. Biochim Biophys Acta. 1107: 245-54. PMID: 1504069
- Merocyanine 540-sensitized photoinactivation of human erythrocytes parasitized by Plasmodium falciparum. | Smith, OM., et al. 1992. Blood. 80: 21-4. PMID: 1611086
- Interaction of Merocyanine 540 with serum albumins: photophysical and binding studies. | Banerjee, M., et al. 2012. J Photochem Photobiol B. 108: 23-33. PMID: 22264940
- Protein interactions of Merocyanine 540: spectroscopic and crystallographic studies with lysozyme as a model protein. | Mitra, P., et al. 2013. J Photochem Photobiol B. 121: 46-56. PMID: 23501729
- Validation of merocyanine 540 staining as a technique for assessing capacitation-related membrane destabilization of fresh dog sperm. | Steckler, D., et al. 2015. Theriogenology. 83: 1451-60. PMID: 25796286
- Merocyanine 540 adsorbed on polyethylenimine-functionalized graphene oxide nanocomposites as a turn-on fluorescent sensor for bovine serum albumin. | Bayraktutan, T. and Meral, K. 2016. Phys Chem Chem Phys. 18: 23400-6. PMID: 27503125
- Disruption of gel phase lipid packing efficiency by sucralose studied with merocyanine 540. | Barker, M. and Kennedy, A. 2017. Colloids Surf B Biointerfaces. 152: 214-219. PMID: 28113123
- Concentration-Driven Fascinating Vesicle-Fibril Transition Employing Merocyanine 540 and 1-Octyl-3-methylimidazolium Chloride. | Dutta, R., et al. 2017. Langmuir. 33: 9811-9821. PMID: 28849933
- Merocyanine 540 as a flow cytometric probe of membrane lipid organization in leukocytes. | McEvoy, L., et al. 1988. J Leukoc Biol. 44: 337-44. PMID: 3183512
- Merocyanine 540, a fluorescent probe sensitive to lipid packing. | Williamson, P., et al. 1983. Biochim Biophys Acta. 732: 387-93. PMID: 6871207
- Use of Merocyanine 540 and Hoechst 33258 for the selective killing of contaminating mycoplasmas in cell cultures. | Tarshis, M., et al. 1994. J Immunol Methods. 168: 245-52. PMID: 7508483
- Merocyanine 540 as a fluorescence indicator for molecular packing stress at the onset of lamellar-hexagonal transition of phosphatidylethanolamine bilayers. | Langner, M. and Hui, SW. 1999. Biochim Biophys Acta. 1415: 323-30. PMID: 9889390
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Merocyanine 540, 100 mg | sc-215303 | 100 mg | $87.00 |