Molecular structure of Mephetyl tetrazole, CAS Number: 916923-10-9
Mephetyl tetrazole (CAS 916923-10-9)
CAS Number:
916923-10-9
Purity:
≥98%
Molecular Weight:
334.41
Molecular Formula:
C20H22N4O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), and no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.
Mephetyl tetrazole (CAS 916923-10-9) References
1. Wu, S., et al., Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1.5 blockers. Bioorg. Med. Chem. Lett., 6213-6218, (2006)Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mephetyl tetrazole, 5 mg | sc-255261 | 5 mg | $149.00 |