Date published: 2025-12-18

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(+)-Menthone (CAS 3391-87-5)

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Alternate Names:
(1S,4R)-p-Menthan-3-one; (2R,5S)-2-Isopropyl-5-methylcyclohexanone
CAS Number:
3391-87-5
Purity:
≥97%
Molecular Weight:
154.25
Molecular Formula:
C10H18O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(+)-Menthone is characterized by a cyclohexane ring with a ketone functional group, giving it distinctive chemical properties conducive to fragrance applications. (+)-Menthone may be used in organic chemistry research due to its reactivity as a ketone, making it a useful component in synthetic transformations and reactions. Its natural occurrence and pleasant scent also make it a useful compound for studying plant biochemistry and the ecological roles of plant volatiles.


(+)-Menthone (CAS 3391-87-5) References

  1. Effect of menthone on the in vitro percutaneous absorption of tamoxifen and skin reversibility.  |  Zhao, K., et al. 2001. Int J Pharm. 219: 177-81. PMID: 11337177
  2. Research on choleretic effect of menthol, menthone, pluegone, isomenthone, and limonene in DanShu capsule.  |  Hu, G., et al. 2015. Int Immunopharmacol. 24: 191-197. PMID: 25499726
  3. Peppermint antioxidants revisited.  |  Riachi, LG. and De Maria, CA. 2015. Food Chem. 176: 72-81. PMID: 25624208
  4. Effect of menthone and related compounds on skin permeation of drugs with different lipophilicity and molecular organization of stratum corneum lipids.  |  Lan, Y., et al. 2016. Pharm Dev Technol. 21: 389-98. PMID: 25684238
  5. Exploring the conformational landscape of menthol, menthone, and isomenthone: a microwave study.  |  Schmitz, D., et al. 2015. Front Chem. 3: 15. PMID: 25815287
  6. Anti-Inflammatory Properties of Menthol and Menthone in Schistosoma mansoni Infection.  |  Zaia, MG., et al. 2016. Front Pharmacol. 7: 170. PMID: 27378927
  7. Biotransformation of (-)-(1R,4S)-Menthone and (+)-(1S,4R)-Menthone by the Common Cutworm Spodoptera litura Larvae.  |  Marumoto, S., et al. 2017. J Oleo Sci. 66: 883-888. PMID: 28701651
  8. The effects of vitamin C and menthone on acyclovir induced DNA damage in rat spermatozoa: An experimental study.  |  Toghiani, S., et al. 2018. Int J Reprod Biomed. 16: 703-710. PMID: 30775686
  9. Cellular Base of Mint Allelopathy: Menthone Affects Plant Microtubules.  |  Sarheed, MM., et al. 2020. Front Plant Sci. 11: 546345. PMID: 33042176
  10. A Natural Plant Ingredient, Menthone, Regulates T Cell Subtypes and Lowers Pro-inflammatory Cytokines of Rheumatoid Arthritis.  |  Chen, X., et al. 2022. J Nat Prod. 85: 1109-1117. PMID: 35302365
  11. Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice.  |  Su, YH. and Lin, JY. 2022. Int J Mol Sci. 23: PMID: 35409371
  12. Menthone supplementation protects from allergic inflammation in the lungs of asthmatic mice.  |  Su, YH. and Lin, JY. 2022. Eur J Pharmacol. 931: 175222. PMID: 35988786
  13. Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application.  |  Zhao, H., et al. 2022. Biomed Pharmacother. 154: 113559. PMID: 35994817
  14. Menthone inhibits type-I interferon signaling by promoting Tyk2 ubiquitination to relieve local inflammation of rheumatoid arthritis.  |  Chen, X., et al. 2022. Int Immunopharmacol. 112: 109228. PMID: 36095947
  15. Menthone Exerts its Antimicrobial Activity Against Methicillin Resistant Staphylococcus aureus by Affecting Cell Membrane Properties and Lipid Profile.  |  Zhao, W., et al. 2023. Drug Des Devel Ther. 17: 219-236. PMID: 36721663

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(+)-Menthone, 1 ml

sc-228448
1 ml
$270.00