Molecular structure of Mensacarcin
Mensacarcin
Application:
Mensacarcin is a cytotoxic, antitumor compound
Molecular Weight:
420.41
Molecular Formula:
C21H24O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Mensacarcin is an antitumor compound (TGI at 1.3 μM) with cytotoxic activity.
Mensacarcin References
- Exploiting the genetic potential of polyketide producing streptomycetes. | Weber, T., et al. 2003. J Biotechnol. 106: 221-32. PMID: 14651864
- Towards a total synthesis of the new anticancer agent mensacarcin: synthesis of the carbocyclic core. | Tietze, LF., et al. 2004. Chemistry. 10: 5233-42. PMID: 15372645
- Cloning and heterologous expression of three type II PKS gene clusters from Streptomyces bottropensis. | Yan, X., et al. 2012. Chembiochem. 13: 224-30. PMID: 22162248
- Functional characterization of different ORFs including luciferase-like monooxygenase genes from the mensacarcin gene cluster. | Maier, S., et al. 2015. Chembiochem. 16: 1175-82. PMID: 25907804
- An influence of the copy number of biosynthetic gene clusters on the production level of antibiotics in a heterologous host. | Manderscheid, N., et al. 2016. J Biotechnol. 232: 110-7. PMID: 27264245
- The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells. | Plitzko, B., et al. 2017. J Biol Chem. 292: 21102-21116. PMID: 29074620
- Generation of a cluster-free Streptomyces albus chassis strains for improved heterologous expression of secondary metabolite clusters. | Myronovskyi, M., et al. 2018. Metab Eng. 49: 316-324. PMID: 30196100
- Bioenergetics underlying single-cell migration on aligned nanofiber scaffolds. | Padhi, A., et al. 2020. Am J Physiol Cell Physiol. 318: C476-C485. PMID: 31875698
- Measurement of Oxygen Consumption Rate (OCR) and Extracellular Acidification Rate (ECAR) in Culture Cells for Assessment of the Energy Metabolism. | Plitzko, B. and Loesgen, S. 2018. Bio Protoc. 8: e2850. PMID: 34285967
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mensacarcin, 1 mg | sc-221881 | 1 mg | $294.00 | |||
Mensacarcin, 5 mg | sc-221881A | 5 mg | $930.00 |