Molecular structure of Menaquinone-1, CAS Number: 957-78-8
Menaquinone-1 (CAS 957-78-8)
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Alternate Names:
2-Methyl-3-(3-methyl-2-butenyl)naphthoquinone; Vitamin MK 1
Application:
Menaquinone-1 is composed of a ring of 2-methyl-1,4-naphthoquinione and one isoprenyl group
CAS Number:
957-78-8
Molecular Weight:
240.30
Molecular Formula:
C16H16O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Menaquinone-1 is composed of a ring of 2-methyl-1,4-naphthoquinione and one isoprenyl group in its side chain. Menaquinones consist of varying numbers of isoprene residues in its side chain and are produced by bacteria. Menaquinone-1, in cell culture studies, has been employed as an antioxidant, showcasing its ability to counteract oxidative stress. Notably, in vitro experiments have revealed its potential to impede the release of inflammatory mediators, including TNF-α and IL-1β.
Menaquinone-1 (CAS 957-78-8) References
- Primary photoreactions of phylloquinone (vitamin K1) and plastoquinone-1 in solution. | Hangarter, MA., et al. 2003. Photochem Photobiol Sci. 2: 524-35. PMID: 12803075
- Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs. | Weinstein, EA., et al. 2005. Proc Natl Acad Sci U S A. 102: 4548-53. PMID: 15767566
- Simple menaquinones reduce carbon tetrachloride and iron (III). | Fu, QS., et al. 2009. Biodegradation. 20: 109-16. PMID: 18594993
- The cytochrome bcc-aa3-type respiratory chain of Rhodococcus rhodochrous. | Kishikawa, J., et al. 2010. J Biosci Bioeng. 110: 42-7. PMID: 20541114
- The bifidogenic growth stimulator inhibits the growth and respiration of Helicobacter pylori. | Nagata, K., et al. 2010. Helicobacter. 15: 422-9. PMID: 21083748
- Synthesis of novel vitamin K2 analogues with modification at the ω-terminal position and their biological evaluation as potent steroid and xenobiotic receptor (SXR) agonists. | Suhara, Y., et al. 2011. J Med Chem. 54: 4269-73. PMID: 21561094
- Purification and characterization of malate:quinone oxidoreductase from thermophilic Bacillus sp. PS3. | Kabashima, Y., et al. 2013. J Bioenerg Biomembr. 45: 131-6. PMID: 23143325
- [The effectiveness of certain magnesium salts in nephrolithiasis caused by the use of sodium oxalate and celecoxib]. | Spasov, AA., et al. 2013. Urologiia. 29-34. PMID: 23662491
- Biotransformation of menadione to its prenylated derivative MK-3 using recombinant Pichia pastoris. | Li, Z., et al. 2017. J Ind Microbiol Biotechnol. 44: 973-985. PMID: 28258406
- Synthesis and Characterization of Partially and Fully Saturated Menaquinone Derivatives. | Koehn, JT., et al. 2018. ACS Omega. 3: 14889-14901. PMID: 31458155
- Metabolite Profiling of the Gut Microbiome in Mice with Dietary Administration of Black Raspberries. | Tu, P., et al. 2020. ACS Omega. 5: 1318-1325. PMID: 32010801
- Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering. | Lee, BM., et al. 2020. PLoS Pathog. 16: e1008287. PMID: 32032366
- The Protective Role of Bioactive Quinones in Stress-induced Senescence Phenotype of Endothelial Cells Exposed to Cigarette Smoke Extract. | Cirilli, I., et al. 2020. Antioxidants (Basel). 9: PMID: 33081423
- Cardiolipin enhances the enzymatic activity of cytochrome bd and cytochrome bo3 solubilized in dodecyl-maltoside. | Asseri, AH., et al. 2021. Sci Rep. 11: 8006. PMID: 33850195
- Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli. | Grund, TN., et al. 2021. Proc Natl Acad Sci U S A. 118: PMID: 34873041
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Menaquinone-1, 100 mg | sc-397212 | 100 mg | $408.00 |