Molecular structure of Melperone hydrochloride, CAS Number: 1622-79-3
Melperone hydrochloride (CAS 1622-79-3)
See product citations (1)
Alternate Names:
1-(4-Fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone hydrochloride
Application:
Melperone hydrochloride is a useful SR-2A receptor antagonist and D2DR inhibitor
CAS Number:
1622-79-3
Purity:
≥98%
Molecular Weight:
299.81
Molecular Formula:
C16H22FNO•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Melperone hydrochloride acts as a dopamine receptor antagonist. It is used to study the role of dopamine receptors in various physiological and pathological processes. Melperone hydrochloride is known to block the binding of dopamine to its receptors, thereby modulating the downstream signaling pathways. Melperone hydrochloride is useful in investigating the mechanisms underlying dopamine-related disorders, such as schizophrenia. Melperone hydrochloride plays a role in advancing our understanding of dopamine receptor function and its implications in various physiological and pathological conditions.
Melperone hydrochloride (CAS 1622-79-3) References
- Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism. | Ichikawa, J., et al. 2002. Brain Res. 956: 349-57. PMID: 12445705
- P-glycoprotein is a factor in the uptake of dextromethorphan, but not of melperone, into the mouse brain: evidence for an overlap in substrate specificity between P-gp and CYP2D6. | Uhr, M., et al. 2004. J Psychopharmacol. 18: 509-15. PMID: 15582917
- Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors. | Seeman, P., et al. 1997. Neuropsychopharmacology. 16: 93-110; discussion 111-35. PMID: 9015795
Inhibitor of:
D2DR, and SR-2A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Melperone hydrochloride, 10 mg | sc-204074 | 10 mg | $64.00 | |||
| US: Only available in the US | ||||||
Melperone hydrochloride, 50 mg | sc-204074A | 50 mg | $325.00 | |||
| US: Only available in the US | ||||||