Meloxicam-d3 (CAS 942047-63-4)
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Meloxicam-d3 is a labeled form of Meloxicam. Meloxicam is a preferential Cox-2 (cyclooxygenase) inhibitor that is used as an anti-inflammatory. The use of deuterated compounds like meloxicam-d3 allows researchers to obtain insights into the metabolic pathways of compounds. The replacement of hydrogen with deuterium can slow down the rate of metabolic degradation, potentially leading to a longer half-life. This characteristic makes meloxicam-d3 valuable for exploring how minor changes in molecular structure can impact a compound′s performance. Moreover, meloxicam-d3 serves as an internal standard in analytical assays, particularly in mass spectrometry-based techniques. The incorporation of deuterium allows for the differentiation of the compound from its non-deuterated counterpart based on mass, facilitating accurate quantification and detection in biological matrices.
Meloxicam-d3 (CAS 942047-63-4) References
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- Pharmacokinetics of Sustained-release, Oral, and Subcutaneous Meloxicam over 72 Hours in Male Beagle Dogs. | Smith, BJ., et al. 2020. J Am Assoc Lab Anim Sci. 59: 737-741. PMID: 32878683
- Using a stable isotope-labeled internal standard for liquid chromatography-tandem mass spectrometry quantitation of meloxicam in human plasma. | Zhan, C., et al. 2021. Biomed Chromatogr. 35: e5217. PMID: 34405424
- Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle. | Castilla-Casadiego, DA., et al. 2022. PLoS One. 17: e0272169. PMID: 35917312
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Meloxicam-d3, 1 mg | sc-218687 | 1 mg | $367.00 |