Meloxicam (CAS 71125-38-7)
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Meloxicam is a compound extensively studied in the context of its effects on prostaglandin synthesis due to its selective inhibition of cyclooxygenase-2 (COX-2), an enzyme implicated in the inflammatory response. In research, meloxicam is utilized to investigate the pathophysiological role of COX-2 in inflammation and pain, as well as in the study of its contribution to carcinogenesis and cardiovascular health. Additionally, meloxicam is employed in comparative studies of various anti-inflammatory compounds to understand their kinetic profiles and mechanisms of action. It offers a valuable means for scientists to explore the selective inhibition of COX-2 versus COX-1. The compound′s attributes allow for further examination of the molecular mechanisms of COX-2 in disease models, contributing to a broader understanding of inflammatory processes and their regulation.
Meloxicam (CAS 71125-38-7) References
- Clinical pharmacokinetics of meloxicam. A cyclo-oxygenase-2 preferential nonsteroidal anti-inflammatory drug. | Davies, NM. and Skjodt, NM. 1999. Clin Pharmacokinet. 36: 115-26. PMID: 10092958
- Meloxicam inhibits rabbit ovulation. | Salhab, AS., et al. 2001. Contraception. 63: 329-33. PMID: 11672556
- Meloxicam. | Fleischmann, R., et al. 2002. Expert Opin Pharmacother. 3: 1501-12. PMID: 12387696
- Effects of some drugs on human erythrocyte 6-phosphogluconate dehydrogenase: an in vitro study. | Akkemik, E., et al. 2010. J Enzyme Inhib Med Chem. 25: 476-9. PMID: 20235752
- Meloxicam as a Radiation-Protective Agent on Mandibles of Irradiated Rats. | Yamasaki, MC., et al. 2017. Braz Dent J. 28: 249-255. PMID: 28492757
- Meloxicam inhibits biofilm formation and enhances antimicrobial agents efficacy by Pseudomonas aeruginosa. | She, P., et al. 2018. Microbiologyopen. 7: PMID: 29178590
- Meloxicam vs robenacoxib for postoperative pain management in dogs undergoing combined laparoscopic ovariectomy and laparoscopic-assisted gastropexy. | Bendinelli, C., et al. 2019. Vet Surg. 48: 578-583. PMID: 30637777
- Dual mechanisms suppress meloxicam bioactivation relative to sudoxicam. | Barnette, DA., et al. 2020. Toxicology. 440: 152478. PMID: 32437779
- Repeated dose of meloxicam induces genotoxicity and histopathological changes in cardiac tissue of mice. | da Silva, JCG., et al. 2022. Drug Chem Toxicol. 45: 822-833. PMID: 32552192
- Administration of meloxicam to improve the welfare of mice in research: a systematic review (2000 - 2020). | Antiorio, ATFB., et al. 2022. Vet Res Commun. 46: 1-8. PMID: 34988874
- Meloxicam can Potentiate the Therapeutic Effects of Synchrotron Microbeam Radiation Therapy on High-Grade Glioma Bearing Rats. | Bouchet, A., et al. 2022. Radiat Res. 197: 655-661. PMID: 35245385
- Changes in rabbit lymphocyte subpopulations and activation following long-term administration of meloxicam. | Hamouzová, P., et al. 2022. Vet Immunol Immunopathol. 253: 110496. PMID: 36174420
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Meloxicam, 20 mg | sc-200626 | 20 mg | $36.00 | |||
Meloxicam, 100 mg | sc-200626A | 100 mg | $94.00 | |||
Meloxicam, 500 mg | sc-200626B | 500 mg | $156.00 |