Molecular structure of Meldonium, CAS Number: 76144-81-5
Meldonium (CAS 76144-81-5)
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Alternate Names:
MET88; Quaterin
Application:
Meldonium is a composition based on a reverse transcriptase inhibitor and meldonium
CAS Number:
76144-81-5
Purity:
>99%
Molecular Weight:
146.19
Molecular Formula:
C6H14N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Mildronate has the ability to modulate energy metabolism and protect cells under conditions of stress. Mildronate is used to study cellular responses to hypoxic conditions. It is thought to mimic some aspects of hypoxic adaptation, which is the process by which cells and tissues adjust to low oxygen environments, making it useful for investigating mechanisms of hypoxia-induced changes in cellular metabolism and function.
Meldonium (CAS 76144-81-5) References
- Meldonium use by athletes at the Baku 2015 European Games. | Stuart, M., et al. 2016. Br J Sports Med. 50: 694-8. PMID: 27015859
- Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses. | Knych, HK., et al. 2017. Drug Test Anal. 9: 1392-1399. PMID: 28513092
- Urinary excretion studies of meldonium after multidose parenteral application. | Forsdahl, G., et al. 2018. J Pharm Biomed Anal. 161: 289-295. PMID: 30189410
- Meldonium improves Huntington's disease mitochondrial dysfunction by restoring peroxisome proliferator-activated receptor γ coactivator 1α expression. | Di Cristo, F., et al. 2019. J Cell Physiol. 234: 9233-9246. PMID: 30362565
- The Effects of Meldonium on the Renal Acute Ischemia/Reperfusion Injury in Rats. | Đurašević, S., et al. 2019. Int J Mol Sci. 20: PMID: 31731785
- Fluorescence chemosensing of meldonium using a cross-reactive sensor array. | Yalcin, E., et al. 2020. Analyst. 145: 3345-3352. PMID: 32226998
- Meldonium determination in milk and meat through UHPLC-HRMS. | Temerdashev, A., et al. 2020. Heliyon. 6: e04771. PMID: 32904324
- The effects of meldonium on the acute ischemia/reperfusion liver injury in rats. | Đurašević, S., et al. 2021. Sci Rep. 11: 1305. PMID: 33446709
- Meldonium residues in milk: A possible scenario for inadvertent doping in sports? | Guddat, S., et al. 2021. Drug Test Anal. 13: 1906-1910. PMID: 34448364
- The Effects of a Meldonium Pre-Treatment on the Course of the Faecal-Induced Sepsis in Rats. | Đurašević, S., et al. 2021. Int J Mol Sci. 22: PMID: 34575863
- Protective Effects of Meldonium in Experimental Models of Cardiovascular Complications with a Potential Application in COVID-19. | Vilskersts, R., et al. 2021. Int J Mol Sci. 23: PMID: 35008470
- The Effects of a Meldonium Pre-Treatment on the Course of the LPS-Induced Sepsis in Rats. | Đurašević, S., et al. 2022. Int J Mol Sci. 23: PMID: 35216510
- Meldonium Ameliorates Hypoxia-Induced Lung Injury and Oxidative Stress by Regulating Platelet-Type Phosphofructokinase-Mediated Glycolysis. | Wang, D., et al. 2022. Front Pharmacol. 13: 863451. PMID: 35450040
- Insights into the pharmacodynamics and pharmacokinetics of meldonium after exposure to acute high altitude. | Liu, F., et al. 2023. Front Pharmacol. 14: 1119046. PMID: 36909160
Inhibitor of:
Acaa1b, ACAD-10, ACAD-11, ACAD-12, ACADVL, acetyl-CoA acyltransferase 2 (ACAA2), ACOT10, ACOT3, ACSM5, ART2B, BBOX1, Carnitine Acetyltransferase, CPTI-M, creatine kinase-M, CROT, DECR1, ECHDC3, ECHS1, HADHA, HADHSC, HIBCH, MCAD, and SLC25A29.Activator of:
CTL2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Meldonium, 100 mg | sc-207887 | 100 mg | $252.00 |