Molecular structure of Melatonin-d4, CAS Number: 66521-38-8
Melatonin-d4 (CAS 66521-38-8)
See product citations (5)
Alternate Names:
Melatonin-d4 is also known as 5-Methoxy-N-acetyltryptamine-d4.
Application:
Melatonin-d4 is an antioxidant and indoleamine neurohormone postulated to mediate photoperiodicity in mammals.
CAS Number:
66521-38-8
Molecular Weight:
236.30
Molecular Formula:
C13H12D4N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Melatonin-d4 is a deuterated version of melatonin, where four hydrogen atoms have been replaced with deuterium, a heavier isotope of hydrogen. Quantification of melatonin by GC or LC-MS analysis can utilize Melatonin-d4 as an internal standard. This distinction is for accurate quantification of melatonin in biological samples, such as plasma, serum, or tissue extracts, where precise measurement of melatonin levels is necessary. By tracing the deuterated compound through various biological matrices, scientists can gain insights into how melatonin is processed. Melatonin is a hormone postulated to mediate photoperiodicity in mammals.
Melatonin-d4 (CAS 66521-38-8) References
- Safety of D-ß-Hydroxybutyrate and Melatonin for the Treatment of Hemorrhagic Shock With Polytrauma. | Wolf, A., et al. 2015. Shock. 44 Suppl 1: 79-89. PMID: 25692249
- Relationship between plasma and salivary melatonin and cortisol investigated by LC-MS/MS. | van Faassen, M., et al. 2017. Clin Chem Lab Med. 55: 1340-1348. PMID: 27997348
- Two indoleamines are secreted from rat pineal gland at night and act on melatonin receptors but are not night hormones. | Lee, BH., et al. 2020. J Pineal Res. 68: e12622. PMID: 31715643
- Nail Melatonin Content: A Suitable Non-Invasive Marker of Melatonin Production. | Gomez-Gomez, A., et al. 2021. Int J Mol Sci. 22: PMID: 33477696
- Liquid chromatography-tandem mass spectrometry measurement of 26 steroid hormones in human serum and plasma samples. | Jia, Y., et al. 2021. J Sep Sci. 44: 2358-2370. PMID: 33835710
- Melatonin increases leaf disease resistance and saponin biosynthesis in Panax notogiseng. | Yang, Q., et al. 2021. J Plant Physiol. 263: 153466. PMID: 34216845
- Melatonin binds with high affinity and specificity to beta-amyloid: LC-MS provides insight into Alzheimer's disease treatment. | Dai, Y., et al. 2021. FEBS Open Bio. 11: 2800-2806. PMID: 34428352
- Effect of circadian system disruption on the concentration and daily oscillations of cortisol, progesterone, melatonin, serotonin, growth hormone, and core body temperature in periparturient dairy cattle. | Suarez-Trujillo, A., et al. 2022. J Dairy Sci. 105: 2651-2668. PMID: 35033342
- Grape-Seed Procyanidin Extract (GSPE) Seasonal-Dependent Modulation of Glucose and Lipid Metabolism in the Liver of Healthy F344 Rats. | Rodríguez, RM., et al. 2022. Biomolecules. 12: PMID: 35740964
- ABCG2 transporter plays a key role in the biodistribution of melatonin and its main metabolites. | Álvarez-Fernández, L., et al. 2023. J Pineal Res. 74: e12849. PMID: 36562106
Inhibitor of:
NOS.Activator of:
MEL-1A-R, and MEL-1B-R.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Melatonin-d4, 2.5 mg | sc-207849 | 2.5 mg | $445.00 | |||
Melatonin-d4, 5 mg | sc-207849B | 5 mg | $455.00 | |||
Melatonin-d4, 10 mg | sc-207849A | 10 mg | $904.00 |