MEK 162 (CAS 606143-89-9)

MEK 162 is a compound that has been the subject of extensive research within the fields of enzymology and signal transduction pathways. In non-clinical research environments, MEK 162 is primarily used to investigate the biochemical mechanisms of the mitogen-activated protein kinase (MAPK) pathway, which is involved in cell proliferation and differentiation. Studies focus on how MEK 162, as a potent inhibitor of MEK1/2 kinases, affects the phosphorylation and activation of downstream proteins such as ERK1/2. Research on MEK 162 includes examining its effects on various cellular processes in vitro, and it serves as a tool to understand the role of the MAPK pathway in cell biology. By inhibiting this pathway, MEK 162 aids in dissecting the signal transduction events that contribute to the regulation of gene expression. Additionally, MEK 162 may be used in the study of kinase-substrate relationships, providing insights into the selectivity and specificity of kinase inhibitors.