Megestrol Acetate CAS: 595-33-5
MF: C24H32O4
MW: 384.51
A progesterone derivative with antineoplastic properties.

Megestrol Acetate (CAS 595-33-5)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 110ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: Megestrol Acetate is a progesterone derivative with antineoplastic properties
CAS Number: 595-33-5
Purity: ≥99%
Molecular Weight: 384.51
Molecular Formula: C24H32O4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Megestrol Acetate is an inhibitor of Androgen Receptor (AR).


References

Sbrams JS, Gutheil J, Aisner J. Oncology. 49 Suppl 2:12-7 (1992). Sedlacek SM. Semin Oncol. 15:3-13 (1988).

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (<1 mg/ml at 25° C), DMSO (33 mg/ml at 25° C), ethanol (15 mg/ml at 25° C), chloroform (1:0.8), and methanol.
Storage :
Store at 4° C
Melting Point :
214-216° C
Boiling Point :
507.07° C
Density :
1.15 g/cm3
Refractive Index :
n20D 1.55
Optical Activity :
α20/D +11°±2°, c = 2 in chloroform; α24/D +5° in chloroform
IC50 :
Progesterone receptor: IC50 = 11 nM (bovine); GR: IC50 = 19 nM (human); Androgen Receptor: IC50 = 30 nM (rat); CYP2C9: IC50 = 10 µM (human); HegG2: IC50 = 260 µM
Ki Data :
Progesterone receptor: Ki= 1.44 nM (bovine); GR: Ki= 8.77 nM (human); Androgen Receptor: Ki= 20 nM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
TU4075000
PubChem CID :
11683
Merck Index :
14: 5805
MDL Number :
MFCD00056470
EC Number :
209-864-5
Beilstein Registry :
1917291
SMILES :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 115ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 11ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.