Molecular structure of MEG (sulfate), CAS Number: 3979-00-8
MEG (sulfate) (CAS 3979-00-8)
Alternate Names:
(2-mercaptoethyl)-guanidine sulfate; Mercaptoethylguanidine hemisulfate salt
Application:
MEG (sulfate) is a selective NOS2 inhibitor
CAS Number:
3979-00-8
Purity:
>98%
Molecular Weight:
336.46
Molecular Formula:
[C3H9N3S]2•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
MEG (sulfate) is a selective scavenger of peroxynitrite and a NOS2 (iNOS) inhibitor. The EC50 values for inhibition of NOS2 (LPS-treated rat lung), NOS3 (eNOS) (bovine endothelial), and NOS1 (nNOS) (rat brain) are 11.5, 110, and 60 muM, respectively. MEG reacts with peroxynitrite with a second order rate constant of 1,900 M-1s-1 at 37degC. MEG (sulfate) also has potent anti-inflammatory activity, which may be due to the combined effect of MEG acting as an inhibitor of NOS2 and as a scavenger of peroxynitrite.
Inhibitor of:
NOS1, NOS2, and NOS3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MEG (sulfate), 5 mg | sc-205381 | 5 mg | $161.00 | |||
MEG (sulfate), 10 mg | sc-205381A | 10 mg | $255.00 |