Med29 Antibody (G-6): sc-390993

Med29 Antibody (G-6) is a mouse monoclonal IgG1 antibody that detects Med29 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Med29, also known as IXL (intersex-like), is a crucial 200 amino acid nuclear protein that serves as a component of the mediator complex, which plays a vital role in regulating transcription by acting as a bridge between transcriptional activators and RNA polymerase II. This interaction is essential for proper gene expression, as Med29 facilitates the assembly of transcription machinery at gene promoters, thereby influencing cellular processes such as differentiation and proliferation. Med29 is widely expressed in both embryonic and adult tissues, highlighting Med29′s importance in various biological contexts. Notably, Med29 has emerged as a novel amplification target gene in pancreatic cancer, indicating Med29′s potential role in tumorigenesis and making Med29 a significant focus for cancer research. The gene encoding Med29 is located on human chromosome 19q13.2, a region known for high gene density, containing approximately 1,400 genes within over 63 million bases, which underscores the complexity and regulatory potential of this chromosomal area.

The preferred Med29 antibody is Med29 Antibody (B-1): sc-393800.