MDL 72832 hydrochloride CAS: 113777-33-6
MF: C22H30N2O4•HCl
MW: 422.95
A post-synaptic 5-HT1A agonist.

MDL 72832 hydrochloride (CAS 113777-33-6)

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Alternate Names: 8-[4-(1,4-Benzodioxan-2-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride
Application: MDL 72832 hydrochloride is a post-synapticSR-1A (5-HT1A receptors) agonist
CAS Number: 113777-33-6
Molecular Weight: 422.95
Molecular Formula: C22H30N2O4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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MDL 72832 hydrochloride is a potent, selective and stereospecific ligand for 5-HT1A receptors which possesses both agonist and antagonist properties. At post-synaptic 5-HT1A receptors, it acts as a specific agonist.


References

1. Mir, A K., et al., 1988. MDL 72832: a potent and stereoselective ligand at central and peripheral 5-HT1A receptors. European journal of pharmacology. 149(1-2): 107-20. PMID: 2840295
2. Millan, M J., et al., 1993. Induction of hypothermia as a model of 5-hydroxytryptamine1A receptor-mediated activity in the rat: a pharmacological characterization of the actions of novel agonists and antagonists. The Journal of pharmacology and experimental therapeutics. 264(3): 1364-76. PMID: 8450471

Physical State :
Solid
Solubility :
Soluble to 5 mM in Water
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
45073438
SMILES :
C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCNCC3COC4=CC=CC=C4O3.Cl

Download SDS (MSDS)

Certificate of Analysis

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