MDA-MB-435S Whole Cell Lysate: sc-364184
- 500 µg protein in 200 µl SDS-PAGE Western blotting buffer
- human whole cell lysate; breast ductal carcinoma cells
- whole cell lysate provided as Western blotting positive control
- should be stored at -20°C and repeated freezing and thawing should be minimized
- sample vial should be placed at 95° C for up to 5 minutes, once prior to use
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SEE ALSO...
MDA-MB-435S whole cell lysate originates from a cell line initially classified as a human breast carcinoma model but later suggested to potentially derive from melanoma. This ambiguity has led to its use in studying cell identity and cross-contamination issues in research. Importantly, the lysate is utilized to explore cancer cell biology, focusing on mechanisms such as metastasis, invasion, and adhesion. Researchers employ this lysate to study the expression and function of integrins and other adhesion molecules, which are critical for cancer cells' ability to migrate and invade tissues. Additionally, MDA-MB-435S lysate is used to examine signal transduction pathways involved in cell survival and proliferation, including those mediated by MAPK and PI3K/Akt pathways. These studies contribute to a broader understanding of the signaling mechanisms that underlie cancer progression and metastasis. The lysate also serves as a tool in the investigation of pharmacological responses to various anti-cancer compounds. By providing insights into cellular responses and protein interactions, MDA-MB-435S lysate aids in the development of research methodologies and the understanding of complex biological processes in cancer cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MDA-MB-435S Whole Cell Lysate | sc-364184 | 500 µg/200 µl | $118.00 |