Date published: 2026-3-17

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MARS2 Antibody (7C3): sc-293382

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Datasheets
  • MARS2 Antibody (7C3) is a mouse monoclonal IgG2a κ MARS2 antibody provided at 100 µg/ml
  • raised against amino acids 1-106 of MARS2 of human origin
  • recommended for detection of MARS2 of human origin by WB, IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MARS2 Antibody (7C3). This work is in progress.
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    MARS2 Antibody (7C3) is a mouse monoclonal IgG2a kappa light chain antibody that detects MARS2 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-MARS2 antibody (7C3) is available as a non-conjugated format. MARS2, also known as methionyl-tRNA synthetase 2, mitochondrial, is a crucial 593 amino acid protein located in the mitochondrial matrix, where MARS2 plays a vital role in protein synthesis by catalyzing the attachment of methionine to its corresponding tRNA. This process is essential for the initiation of protein translation, making MARS2 critical for mitochondrial function and overall cellular health. The gene encoding MARS2 is situated on human chromosome 2q33.1, which is significant as this chromosome is the second largest in the human genome and harbors numerous genes associated with various genetic disorders. Mutations in MARS2 can lead to mitochondrial dysfunction, which has been implicated in a range of diseases, highlighting the importance of studying MARS2 for understanding mitochondrial pathologies. MARS2 monoclonal antibody (7C3) is an invaluable tool for researchers investigating the role of mitochondrial proteins in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    MARS2 Antibody (7C3) References:

    1. An ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamily maps to human chromosome 2p21 in the region of the Sitosterolemia locus.  |  Shulenin, S., et al. 2001. Cytogenet Cell Genet. 92: 204-8. PMID: 11435688
    2. Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndrome.  |  Hearn, T., et al. 2002. Nat Genet. 31: 79-83. PMID: 11941370
    3. Characterization of the human mitochondrial methionyl-tRNA synthetase.  |  Spencer, AC., et al. 2004. Biochemistry. 43: 9743-54. PMID: 15274629
    4. Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis.  |  Kelsell, DP., et al. 2005. Am J Hum Genet. 76: 794-803. PMID: 15756637
    5. Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS.  |  Bonnefond, L., et al. 2005. Biochemistry. 44: 4805-16. PMID: 15779907
    6. Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21.  |  Patel, SB., et al. 1998. J Clin Invest. 102: 1041-4. PMID: 9727073

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    MARS2 Antibody (7C3)

    sc-293382
    100 µg/ml
    $322.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with MARS2 (7C3): sc-293382 antibody?

    Asked by: jenniferc
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
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    Rated 5 out of 5 by from Good for Western blotAntibody detects human MARS2 in MCF-7 cell lysate by Western blot. -SCBT QC
    Date published: 2023-09-14
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    MARS2 Antibody (7C3) is rated 5.0 out of 5 by 1.
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