MARCH10 Antibody (55-Y): sc-100510
- MARCH10 Antibody (55-Y) is a mouse monoclonal IgG1 κ MARCH10 antibody provided at 100 µg/ml
- raised against recombinant MARCH10 of human origin
- recommended for detection of MARCH10 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MARCH10 Antibody (55-Y). This work is in progress.
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MARCH10 Antibody (55-Y) is a mouse monoclonal IgG1 kappa light chain antibody that detects MARCH10 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-MARCH10 antibody (55-Y) is available as the non-conjugated form. MARCH10 protein, also known as membrane-associated ring finger (C3HC4) 10 or RNF190, is an 808 amino acid protein characterized by a RING-CH-type zinc finger domain, which plays a crucial role in the ubiquitination pathway, a vital process for protein degradation and cellular regulation. MARCH10 (55-Y) monoclonal antibody enables research into protein degradation mechanisms and MARCH10′s role in cellular processes, making this antibody valuable for studies related to cancer, immune response, and diseases where protein regulation is disrupted.
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MARCH10 Antibody (55-Y) References:
- MARCH-XI, a novel transmembrane ubiquitin ligase implicated in ubiquitin-dependent protein sorting in developing spermatids. | Morokuma, Y., et al. 2007. J Biol Chem. 282: 24806-15. PMID: 17604280
- MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation. | De Gassart, A., et al. 2008. Proc Natl Acad Sci U S A. 105: 3491-6. PMID: 18305173
- Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes. | Thibodeau, J., et al. 2008. Eur J Immunol. 38: 1225-30. PMID: 18389477
- The trafficking and regulation of membrane receptors by the RING-CH ubiquitin E3 ligases. | Nathan, JA. and Lehner, PJ. 2009. Exp Cell Res. 315: 1593-600. PMID: 19013150
- Interplay between poxviruses and the cellular ubiquitin/ubiquitin-like pathways. | Zhang, L., et al. 2009. FEBS Lett. 583: 607-14. PMID: 19174161
- Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. | Gauci, S., et al. 2009. Anal Chem. 81: 4493-501. PMID: 19413330
- Role of the RING-CH domain of viral ligase mK3 in ubiquitination of non-lysine and lysine MHC I residues. | Herr, RA., et al. 2009. Traffic. 10: 1301-17. PMID: 19531064
- Cutting edge: requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells. | Ohmura-Hoshino, M., et al. 2009. J Immunol. 183: 6893-7. PMID: 19917682
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MARCH10 Antibody (55-Y) | sc-100510 | 100 µg/ml | $322.00 | |||
MARCH10 Antibody (55-Y): m-IgG Fc BP-HRP Bundle | sc-551878 | 100 µg Ab; 10 µg BP | $361.00 |