MAP kinase substrate (MBP)
See product citations (8)
Alternate Names:
MAP Kinase Substrate 2 (Myelin Basic Protein 90-98); APRTPGGRR; MBP MAPK Substrate
Application:
MAP kinase substrate (MBP) is a peptide substrate for ERK 1 and ERK 2 MAP kinases
Purity:
≥95% pure by HPLC
Molecular Weight:
967.1
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
MAP kinase substrate (MBP) is a peptide substrate for ERK 1 and ERK 2 MAP kinases. Sequence contains amino acids 95-98 of myelin basic protein (MBP) including Thr 97 within the Pro-X-Ser/Thr-Pro MAP kinase substrate consensus sequence phosphorylation site.
MAP kinase substrate (MBP) References
- Characterization of fertilization-modulated myelin basic protein kinases from sea star: regulation of Mapk. | Lefebvre, DL., et al. 1999. J Cell Biochem. 75: 272-87. PMID: 10502300
- MAP kinase 1/2 (Erk 1/2) and serine/threonine specific protein kinase Akt/PKB expression and activity in the human corpus cavernosum. | Sommer, F., et al. 2002. Int J Impot Res. 14: 217-25. PMID: 12152110
- Determination of protein phosphorylation by extracellular signal-regulated kinase using capillary electrophoresis and matrix-assisted laser desorption ionization time-of-flight mass spectrometry. | Nam, HS., et al. 2002. J Chromatogr A. 976: 79-85. PMID: 12462598
- Activation and phosphorylation on Thr-160 of nuclear-targeted CDK2 Is ERK dependent. | Lents, NH., et al. 2002. Ann N Y Acad Sci. 973: 265-7. PMID: 12485874
- Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase. | Clark-Lewis, I., et al. 1991. J Biol Chem. 266: 15180-4. PMID: 1907971
- Recombinant IL-6 activates p42 and p44 mitogen-activated protein kinases in the IL-6 responsive B cell line, AF-10. | Daeipour, M., et al. 1993. J Immunol. 150: 4743-53. PMID: 8388418
- Activation of mitogen-activated protein kinase/ERK-2 in phytohaemagglutin in blasts by recombinant interleukin-2: contrasting features with CD3 activation. | Fairhurst, RM., et al. 1993. Immunology. 79: 112-8. PMID: 8389729
- Stimulation of mitogen activated protein kinase by LDL and oxLDL in human U-937 macrophage-like cells. | Deigner, HP. and Claus, R. 1996. FEBS Lett. 385: 149-53. PMID: 8647240
- Activation of MAP kinases and phosphorylation of caldesmon in canine colonic smooth muscle. | Gerthoffer, WT., et al. 1996. J Physiol. 495 (Pt 3): 597-609. PMID: 8887769
- Activation of MAP kinases in airway smooth muscle. | Gerthoffer, WT., et al. 1997. Am J Physiol. 272: L244-52. PMID: 9124375
- The activation of MAP kinase during vertical palatal shelf development in hamster. | Young, AV., et al. 1997. Growth Dev Aging. 61: 27-38. PMID: 9129968
- A new peptide conjugate as a highly specific substrate for MAP kinase. | Kameshita, I., et al. 1997. J Biochem. 122: 168-72. PMID: 9276684
- Modulation of rat rotational behavior by direct gene transfer of constitutively active protein kinase C into nigrostriatal neurons. | Song, S., et al. 1998. J Neurosci. 18: 4119-32. PMID: 9592092
Substrate of:
Enzyme, ERK 1, and ERK 2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MAP kinase substrate (MBP), 1 mg | sc-3011 | 1 mg | $95.00 |