MAO-B Antibody (B-8): sc-515575

MAO-B Antibody (B-8) is a mouse monoclonal IgG2a antibody that detects monoamine oxidase B (MAO-B) in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). MAO-B is an essential enzyme located in the mitochondrial outer membrane, where MAO-B plays a crucial role in the oxidative deamination of biogenic amines, particularly in the degradation of phenylethylamine and benzylamine. This enzymatic activity is vital for maintaining neurotransmitter balance in the brain, as MAO-B helps regulate levels of various amines that are critical for mood and cognitive function. MAO-B presence in platelets and the brain highlights MAO-B importance in both peripheral and central nervous system functions, making MAO-B a significant focus in psychiatric research, particularly concerning conditions like depression and schizophrenia. Notably, variations in MAO-B activity have been associated with genetic predispositions to these mental health disorders, underscoring MAO-B relevance in both clinical and genetic studies. The genes encoding MAO-A and MAO-B are located on human chromosome Xp11.23, further emphasizing MAO-B roles in health and disease. Anti-MAO-B antibody (B-8) is an invaluable tool for researchers investigating the biochemical pathways involving monoamine oxidases and their implications in neuropsychiatric conditions.

The preferred MAO-B antibody is MAO-B Antibody (D-6): sc-515354.