Mannide Monooleate (CAS 9049-98-3)

Mannide monooleate is a nonionic surfactant derived from the esterification of mannide (a dehydrated form of mannitol) with oleic acid. Its amphiphilic nature, characterized by a hydrophilic mannide head and a hydrophobic oleate tail, enables it to reduce surface tension and form stable emulsions and dispersions. This surfactant is extensively utilized in research applications focused on the stabilization and solubilization of hydrophobic compounds, making it valuable for studies in materials science and biochemistry. In biochemical research, mannide monooleate is used to solubilize membrane proteins and lipids, facilitating their extraction and purification without denaturing them. This capability is critical for structural and functional studies of membrane-associated proteins, where maintaining native conformations is essential. Additionally, it is employed in the preparation of liposomes and other vesicular systems, which serve as model membranes for investigating lipid-protein interactions and the dynamics of membrane processes. Mannide monooleate′s emulsifying properties are also harnessed in the development of stable emulsions for various research purposes, including the study of drug delivery mechanisms and the encapsulation of bioactive compounds. Its ability to form micelles and stabilize colloidal systems is exploited in formulating nanoparticles and other nanostructures, aiding in the controlled assembly and characterization of these materials. Overall, mannide monooleate plays a crucial role in advancing our understanding of membrane biophysics, protein chemistry, and the development of novel materials in research contexts.