Date published: 2026-2-2

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Maltotetraitol (CAS 66767-99-5)

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Alternate Names:
α-D-glucopyranosyl-(1-4)-α-D-glucopyranosyl-(1-4)-a-D-glucopyranosyl-(1-4)-D-glucitol
CAS Number:
66767-99-5
Purity:
≥95%
Molecular Weight:
668.59
Molecular Formula:
C24H44O21
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Maltotetraitol, a disaccharide composed of four glucose molecules interconnected by glycosidic bonds, serves as a valuable substrate in examining carbohydrate metabolism-related enzymes, including maltase and amylase. It also acts as a substrate for investigating carbohydrate uptake transporters, like the maltose transporter. Furthermore, maltotetraitol finds utility in elucidating the structure and functionality of carbohydrates, specifically the glycosidic bonds linking glucose molecules.


Maltotetraitol (CAS 66767-99-5) References

  1. Crystal structures of the maltodextrin/maltose-binding protein complexed with reduced oligosaccharides: flexibility of tertiary structure and ligand binding.  |  Duan, X., et al. 2001. J Mol Biol. 306: 1115-26. PMID: 11237621
  2. Structural evidence for a dominant role of nonpolar interactions in the binding of a transport/chemosensory receptor to its highly polar ligands.  |  Duan, X. and Quiocho, FA. 2002. Biochemistry. 41: 706-12. PMID: 11790091
  3. Structural characterization of neutral oligosaccharide mixtures through a combination of capillary electrochromatography and ion trap tandem mass spectrometry.  |  Que, AH. and Novotny, MV. 2003. Anal Bioanal Chem. 375: 599-608. PMID: 12638042
  4. Evaluation of the relative stability of liganded versus ligand-free protein conformations using Simplicial Neighborhood Analysis of Protein Packing (SNAPP) method.  |  Sherman, DB., et al. 2004. Proteins. 56: 828-38. PMID: 15281134
  5. Dextran dextrinase and dextran of Gluconobacter oxydans.  |  Naessens, M., et al. 2005. J Ind Microbiol Biotechnol. 32: 323-34. PMID: 15973532
  6. Action pattern of alpha-amylase from Aspergillus oryzae in concentrated media.  |  Graber, M. and Combes, D. 1990. Biotechnol Bioeng. 36: 12-8. PMID: 18592604
  7. The pH dependence of the action pattern in porcine pancreatic alpha-amylase-catalyzed reaction for maltooligosaccharide substrates.  |  Ishikawa, K., et al. 1991. Arch Biochem Biophys. 289: 124-9. PMID: 1898059
  8. Freeze-drying of proteins with glass-forming oligosaccharide-derived sugar alcohols.  |  Kadoya, S., et al. 2010. Int J Pharm. 389: 107-13. PMID: 20097277
  9. The molecular basis of glycogen breakdown and transport in Streptococcus pneumoniae.  |  Abbott, DW., et al. 2010. Mol Microbiol. 77: 183-99. PMID: 20497336
  10. Structure of Streptomyces maltosyltransferase GlgE, a homologue of a genetically validated anti-tuberculosis target.  |  Syson, K., et al. 2011. J Biol Chem. 286: 38298-38310. PMID: 21914799
  11. Role of water in ligand binding to maltose-binding protein: insight from a new docking protocol based on the 3D-RISM-KH molecular theory of solvation.  |  Huang, W., et al. 2015. J Chem Inf Model. 55: 317-28. PMID: 25545470
  12. Assessment of Dimeric Metal-Glycan Adducts via Isotopic Labeling and Ion Mobility-Mass Spectrometry.  |  Morrison, KA., et al. 2018. J Am Soc Mass Spectrom. 29: 1638-1649. PMID: 29802562
  13. Inspection of active sites of human salivary alpha-amylase isozymes by means of non-reducing-end substituted maltooligosaccharides with 2-pyridylamino residue.  |  Omichi, K. and Ikenaka, T. 1986. J Biochem. 99: 1245-52. PMID: 3486866
  14. Inhibition of human digestive enzymes by hydrogenated malto-oligosaccharides.  |  Würsch, P. and Del Vedovo, S. 1981. Int J Vitam Nutr Res. 51: 161-5. PMID: 6169675
  15. Two modes of ligand binding in maltose-binding protein of Escherichia coli. Electron paramagnetic resonance study of ligand-induced global conformational changes by site-directed spin labeling.  |  Hall, JA., et al. 1997. J Biol Chem. 272: 17610-4. PMID: 9211909

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Maltotetraitol, 25 mg

sc-286150
25 mg
$530.00

Maltotetraitol, 50 mg

sc-286150A
50 mg
$1072.00