Malonic acid-2-13C (CAS 55514-11-9)

Malonic acid-2-13C is a stable isotope-labeled compound that plays a role in metabolic processes within the cell. As a dicarboxylic acid, it is involved in the tricarboxylic acid (TCA) cycle, known as the citric acid cycle, which is a central metabolic pathway for the production of energy in the form of adenosine triphosphate (ATP). Malonic acid-2-13C participates in the TCA cycle by serving as a precursor for the synthesis of succinate, a key intermediate in the cycle. Malonic acid-2-13C is incorporated into succinate through a series of enzymatic reactions, ultimately contributing to the generation of reducing equivalents such as NADH and FADH2, which are essential for ATP production through oxidative phosphorylation. Malonic acid-2-13C can be utilized in the biosynthesis of various cellular components, including fatty acids and sterols, further highlighting its importance in cellular metabolism. The presence of malonic acid-2-13C influences cellular processes by directly impacting the flow of carbon through the TCA cycle and its interconnected metabolic pathways, ultimately contributing to the maintenance of cellular energy homeostasis and the synthesis of essential biomolecules.