Molecular structure of Maleimide-PEG2-NHS
Maleimide-PEG2-NHS (CAS 955094-26-5)
Alternate Names:
Succinimide-Maleimide PEG
Application:
Maleimide-PEG2-NHS is a heterobifunctional amine- and sulfhydryl-reactive crosslinker, 17.6 angstrom ethylene oxide spacer arm
CAS Number:
955094-26-5
Molecular Weight:
425.39
Molecular Formula:
C18H23N3O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Maleimide-PEG2-NHS is a heterobifunctional amine- and sulfhydryl-reactive crosslinker with a 17.6 angstrom ethylene oxide spacer arm. Maleimide-PEG2-NHS is a chemical compound used in bioconjugation and protein labeling applications. It is a derivative of polyethylene glycol (PEG) that contains a maleimide functional group and an N-hydroxysuccinimide (NHS) ester. The maleimide group selectively reacts with sulfhydryl (-SH) groups of cysteine residues in proteins, allowing for site-specific conjugation. The NHS ester enhances the reactivity of the maleimide group towards primary amines, enabling the coupling of proteins or other molecules containing primary amines.
Maleimide-PEG,[object Object],-NHS (CAS 955094-26-5) References
- Design of siRNA Bioconjugates for Efficient Control of Cancer-Associated Membrane Receptors. | Lee, JW., et al. 2023. ACS Omega. 8: 36435-36448. PMID: 37810687
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Maleimide-PEG2-NHS, 50 mg | sc-397274 | 50 mg | $178.00 | |||
Maleimide-PEG2-NHS, 250 mg | sc-397274A | 250 mg | $510.00 |