Date published: 2025-10-12

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Maleic acid (CAS 110-16-7)

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Alternate Names:
Toxilic acid
CAS Number:
110-16-7
Purity:
≥99%
Molecular Weight:
116.07
Molecular Formula:
C4H4O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Maleic acid is a dicarboxylic acid that is often utilized in research as a building block in the synthesis of a variety of polymers, resins, and copolymers, due to its unsaturated bond which provides sites for polymerization reactions. In the field of organic synthesis, it serves as a dienophile in Diels-Alder reactions, a widely studied mechanism for forming six-membered rings, which are common in many natural products and industrial chemicals. Researchers also utilize maleic acid′s chelating ability to study its interactions with various metal ions, which is relevant in the development of new materials and catalysis.


Maleic acid (CAS 110-16-7) References

  1. Final report on the safety assessment of Maleic Acid.  |  ,. 2007. Int J Toxicol. 26 Suppl 2: 125-30. PMID: 17613135
  2. Pharmacokinetics of Maleic Acid as a Food Adulterant Determined by Microdialysis in Rat Blood and Kidney Cortex.  |  Hou, ML., et al. 2016. Molecules. 21: 367. PMID: 26999094
  3. Maleic acid treatment of biologically detoxified corn stover liquor.  |  Kim, D., et al. 2016. Bioresour Technol. 216: 437-45. PMID: 27262718
  4. Synthesis of Caffeine/Maleic Acid Co-crystal by Ultrasound-assisted Slurry Co-crystallization.  |  Apshingekar, PP., et al. 2017. J Pharm Sci. 106: 66-70. PMID: 28029342
  5. Maleic acid modified cellulose for scavenging lead from water.  |  Vadakkekara, GJ., et al. 2019. Int J Biol Macromol. 129: 293-304. PMID: 30742922
  6. Novel Maleic Acid, Crosslinked, Nanofibrous Chitosan/Poly (Vinylpyrrolidone) Membranes for Reverse Osmosis Desalination.  |  Ali, I., et al. 2020. Int J Mol Sci. 21: PMID: 33020456
  7. One-pot fractionation of corn stover with peracetic acid and maleic acid.  |  Lyu, Q., et al. 2021. Bioresour Technol. 320: 124306. PMID: 33157440
  8. Evaluation of Fumaric Acid and Maleic Acid as Internal Standards for NMR Analysis of Protein Precipitated Plasma, Serum, and Whole Blood.  |  Nagana Gowda, GA., et al. 2021. Anal Chem. 93: 3233-3240. PMID: 33538164
  9. Development of a maleic acid-based material to selectively solid-phase extract basic compounds from environmental samples.  |  Fontanals, N., et al. 2021. J Chromatogr A. 1647: 462165. PMID: 33945931
  10. Inhibition of Oomycetes by the Mixture of Maleic Acid and Copper Sulfate.  |  Yeon, J., et al. 2022. Plant Dis. 106: 960-965. PMID: 34705489
  11. Effect of Maleic Acid Root Conditioning on Release of Transforming Growth Factor Beta 1 from Infected Root Canal Dentin.  |  Ballal, NV., et al. 2022. J Endod. 48: 620-624. PMID: 35217129
  12. Formation of styrene maleic acid lipid nanoparticles (SMALPs) using SMA thin film on a substrate.  |  Gordon, EA., et al. 2022. Anal Biochem. 647: 114692. PMID: 35461801
  13. Pretreatment with dilute maleic acid enhances the enzymatic digestibility of sugarcane bagasse and oil palm empty fruit bunch fiber.  |  Risanto, L., et al. 2023. Bioresour Technol. 369: 128382. PMID: 36423754

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Maleic acid, 250 g

sc-250287
250 g
$26.00