Date published: 2026-5-26

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Malathion β-monoacid (CAS 1642-51-9)

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Alternate Names:
2-[(Dimethoxyphosphinothioyl)thio]butanedioic Acid 1-Ethyl Ester Malathion β-Monocarboxylic Acid; O,O-Dimethyl S-(1-Carbethoxy-2-carboxy)ethyl Phosphorodithioate; S-[2-Carboxy-1-(ethoxycarbonyl)ethyl]O,O-di-methyl Phosphorodithioate
CAS Number:
1642-51-9
Molecular Weight:
302.30
Molecular Formula:
C8H15O6PS2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Malathion β-monoacid plays a vital role as a precursor for developing phosphorothioate analogs of nucleotides. Acting as a nucleophile, this phosphorothioate ester participates in diverse reactions, including the formation of phosphorothioate esters when reacting with electrophiles like alkyl halides. Additionally, Malathion β-monoacid reacts with aldehydes and ketones to yield β-hydroxy phosphorothioate esters.


Malathion β-monoacid (CAS 1642-51-9) References

  1. Chemoenzymatic resolution of rac-malathion.  |  Hitt, DM., et al. 2014. Tetrahedron Asymmetry. 25: 529-533. PMID: 24839353
  2. Effects of malathion metabolites on degranulation of and mediator release by human and rat basophilic cells.  |  Xiong, S. and Rodgers, K. 1997. J Toxicol Environ Health. 51: 159-75. PMID: 9176556

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Malathion β-monoacid, 10 mg

sc-491089
10 mg
$380.00