Mal-PEG4-NHS ester (CAS 1325208-25-0)
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Mal-PEG4-NHS ester, or N-methoxypolyethylene glycol-4-N-hydroxysuccinimide ester, is a polyethylene glycol (PEG) derivative extensively employed in bioconjugation and protein engineering. This versatile reagent finds wide application in biochemistry, biotechnology, and medical research, serving to link or conjugate molecules together. Mal-PEG4-NHS ester offers distinct advantages over other PEG derivatives, such as its capacity to form stable linkages, low toxicity, and versatility across various applications. It enables the conjugation of proteins, peptides, nucleic acids, and diverse molecules, while also facilitating the synthesis of bioconjugates and preparation of nanoparticles. The mechanism of action of Mal-PEG4-NHS ester involves the formation of a robust amide bond between the NHS and the malonate group of the PEG chain. This bond exhibits resistance to hydrolysis, thereby enabling effective linkage between two molecules.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Mal-PEG4-NHS ester, 100 mg | sc-496142 | 100 mg | $525.00 |