Molecular structure of Makisterone A, CAS Number: 20137-14-8
Makisterone A (CAS 20137-14-8)
See product citations (6)
Application:
Makisterone A is a member of the ecdysteroid compound class
CAS Number:
20137-14-8
Purity:
≥95%
Molecular Weight:
494.66
Molecular Formula:
C28H46O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Makisterone A is a synthetic steroid hormone derived from progesterone. This compound operates by binding to androgen receptors present in the body. Through this binding process, a sequence of intricate biochemical reactions is initiated, resulting in the synthesis of a variety of hormones and proteins. These newly formed hormones and proteins then proceed to interact with different tissues and organs in the body, leading to a diverse range of biochemical and physiological effects.
Makisterone A (CAS 20137-14-8) References
- Separation of ecdysterone, inokosterone, makisterone A, alpha-ecdysone and ponasterone A by a combination of adsorptive and reversed-phase liquid chromatography. | Gilgan, MW. 1976. J Chromatogr. 129: 447-50. PMID: 1002801
- Ecdysteroids of quinoa seeds (Chenopodium quinoa Willd.). | Zhu, N., et al. 2001. J Agric Food Chem. 49: 2576-8. PMID: 11368638
- Inhibition of [3H]ponasterone A binding by ecdysone agonists in the intact Kc cell line. | Nakagawa, Y., et al. 2002. Insect Biochem Mol Biol. 32: 175-80. PMID: 11755060
- Makisterone A:a 28-carbon hexahydroxy molting hormone from the embryo of the milkweed bug. | Kaplanis, JN., et al. 1975. Science. 190: 681-2. PMID: 1237931
- Evidence for the presence of makisterone A in Drosophila larvae and the secretion of 20-deoxymakisterone A by the ring gland. | Redfern, CP. 1984. Proc Natl Acad Sci U S A. 81: 5643-7. PMID: 16593512
- An ecdysone receptor from the pentatomomorphan, Nezara viridula, shows similar affinities for moulting hormones makisterone A and 20-hydroxyecdysone. | Tohidi-Esfahani, D., et al. 2011. Insect Biochem Mol Biol. 41: 77-89. PMID: 21035548
- LC/MS/MS identification of 20-hydroxyecdysone in a scorpion (Liocheles australasiae) and its binding affinity to in vitro-translated molting hormone receptors. | Miyashita, M., et al. 2011. Insect Biochem Mol Biol. 41: 932-7. PMID: 21958716
- The ecdysteroidome of Drosophila: influence of diet and development. | Lavrynenko, O., et al. 2015. Development. 142: 3758-68. PMID: 26395481
- Fat body lipolysis connects poor nutrition to hypopharyngeal gland degradation in Apis mellifera. | Corby-Harris, V., et al. 2019. J Insect Physiol. 116: 1-9. PMID: 30953617
- Cocculus hirsutus-Derived Phytopharmaceutical Drug Has Potent Anti-dengue Activity. | Shukla, R., et al. 2021. Front Microbiol. 12: 746110. PMID: 34912307
- Makisterone A attenuates experimental cholestasis by activating the farnesoid X receptor. | Kang, P. and Li, S. 2022. Biochem Biophys Res Commun. 623: 162-169. PMID: 35921707
- Paper chromatographic separation of alpha-ecdysone, ecdysterone, inokosterone, makisterone A and ponasterone A. | Gilgan, MW. and Farquharson, TE. 1973. Steroids. 22: 365-72. PMID: 4747441
- RH-5849, a nonsteroidal ecdysone agonist, does not mimic makisterone-A in Dysdercus koenigii. | Koul, O. and Kapil, RS. 1994. Experientia. 50: 461-4. PMID: 8194581
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Makisterone A, 250 µg | sc-202218 | 250 µg | $51.00 | |||
Makisterone A, 1 mg | sc-202218A | 1 mg | $112.00 | |||
Makisterone A, 100 mg | sc-202218B | 100 mg | $6248.00 | |||
Makisterone A, 500 mg | sc-202218C | 500 mg | $16646.00 | |||
Makisterone A, 1 g | sc-202218D | 1 g | $27411.00 |